17482-05-2

Basic information

• Product Name: 2-CHLOROPHENYL METHYL SULFONE
• Synonyms: 1-Chloro-2-(methylsulfonyl)benzene, 2-Chlorphenyl-methylsulfon;1-Chloro-2-(methylsulphonyl)benzene;2-Chlorphenyl-methylsulfon;2-Chlorophenylmethylsulphone99%
• CAS NO: 17482-05-2
• Molecular Formula: C₇H₇ClO₂S
• Molecular Weight: 0
• Mol File: 17482-05-2.mol
• Article Data: 24

Chemical Properties

• Melting Point: 90-94 °C
• Boiling Point: 340.3 °C at 760 mmHg
• Flash Point: 159.6 °C
• Appearance: /
• Density: 1.331 g/cm³
• Vapor Pressure: 0.000171mmHg at 25°C
• Refractive Index: 1.541
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-CHLOROPHENYL METHYL SULFONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLOROPHENYL METHYL SULFONE(17482-05-2)
• EPA Substance Registry System: 2-CHLOROPHENYL METHYL SULFONE(17482-05-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22-41
• Safety Statements: 26-36/39
• WGK Germany: 3
• Hazardous Substances Data: 17482-05-2(Hazardous Substances Data)

Usage

General Description

2-Chlorophenyl methyl sulfone, also known as 2-chloro-4-methylsulfonyl benzene, is a chemical compound with the molecular formula C7H7ClO2S. It is a sulfone compound that consists of a phenyl ring with a methylsulfonyl group and a chlorine atom attached. 2-CHLOROPHENYL METHYL SULFONE is used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It has also been used as an intermediate in the production of dyes, pigments, and other organic compounds. 2-Chlorophenyl methyl sulfone is a colorless to pale yellow solid that is soluble in organic solvents and can be hazardous if ingested, inhaled, or in contact with the skin.

InChI:InChI=1/C7H7ClO2S/c1-11(9,10)7-5-3-2-4-6(7)8/h2-5H,1H3

Upstream product

• 558-25-8 methyl fluorosulfonate 
• 108-90-7 chlorobenzene 
• 2987-49-7 2-(methylsulfonyl)aniline 
• 34560-81-1 ortho-chlorophenyl n-propyl sulfide 
• 32503-27-8 tetra(n-butyl)ammonium hydrogensulfate 
• 5906-98-9 N-amino-o-chlorobenzenesulfonamide 
• 868-85-9 Dimethyl phosphite 
• 110-05-4 di-tert-butyl peroxide 
• 15946-36-8 2-chlorobenzenesulfinic acid sodium salt 
• 17733-22-1 2-chlorothioanisole 
• 95-50-1 1,2-dichloro-benzene 
• 60036-47-7 o-methylsulphonylphenyl methyl sulphide 
• 75-75-2 methanesulfonic acid 
• 6320-03-2 2-chlorothiphenol 

Downstream Products

• 13736-79-3 1-methanesulfonyl-2-methoxy-benzene 
• 19760-91-9 o-Ethoxy-phenylmethylsulfon 
• 60036-47-7 o-methylsulphonylphenyl methyl sulphide 
• 60036-44-4 1,2-bis(methanesulfonyl)benzene 
• 89265-35-0 2-Methanesulfonyl-benzenesulfonyl chloride 
• 282719-68-0 benzyl o-methylsulfonylphenyl sulfide 
• 202286-70-2 7,8,10,12-tetramethyl-3-(phenylsulfonyl)benzoheptalene-2,4-diol 

Relevant articles and documents

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Flow Electrosynthesis of Sulfoxides, Sulfones, and Sulfoximines without Supporting Electrolytes

An efficient electrochemical flow process for the selective oxidation of sulfides to sulfoxides and sulfones and of sulfoxides toN-cyanosulfoximines has been developed. In total, 69 examples of sulfoxides, sulfones, andN-cyanosulfoximines have been synthesized in good to excellent yields and with high current efficiencies. The synthesis was assisted and facilitated through a supporting electrolyte-free, fully automated electrochemical protocol that highlights the advantages of flow electrolysis.

A novel synthesis of aryl methyl sulfones and β-hydroxysulfones from sodium sulfinates and di-tert-butyl peroxide in H2O medium

A novel and convenient synthetic route for aryl methyl sulfones and β-hydroxysulfones was developed via the radical reaction between sodium sulfinates and di-tert-butyl peroxide (DTBP). Without any catalysts and additives, the synthetic process could be smoothly carried out to afford the target products in good to excellent yields in H2O medium, demonstrating its promising application. In the present system, H2O could act not only as a green solvent but also as a reactant.