17583-00-5

Basic information

• Product Name: 2-(phenylamino)benzonitrile
• CAS NO: 17583-00-5
• Molecular Formula: C₁₃H₁₀N₂
• Molecular Weight: 194.2319
• Mol File: 17583-00-5.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 353.1°C at 760 mmHg
• Flash Point: 167.4°C
• Density: 1.15g/cm³
• Vapor Pressure: 3.66E-05mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: 2-(phenylamino)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(phenylamino)benzonitrile(17583-00-5)
• EPA Substance Registry System: 2-(phenylamino)benzonitrile(17583-00-5)

Safety Data

• Hazardous Substances Data: 17583-00-5(Hazardous Substances Data)

Usage

Physical form

white to light yellow crystalline powder

Common uses

+ precursor in the synthesis of various organic substances
+ building block in the production of dyes, pigments, and pharmaceutical compounds
+ use in the field of organic electronics (e.g. OLEDs, organic photovoltaic cells)

Potential biological activities

+ anti-inflammatory properties
+ analgesic properties

Ongoing research

for potential therapeutic applications

Upstream product

• 873-32-5 2-Chlorobenzonitrile 
• 62-53-3 aniline 
• 1885-29-6 anthranilic acid nitrile 
• 98-80-6 phenylboronic acid 
• 612-24-8 o-nitrobenzonitrile 
• 55305-43-6 N-cyano-N-phenyl-p-toluenesulfonamide 
• 382165-80-2 N-nitrosodiphenylamine 
• 2042-37-7 o-cyanobromobenzene 
• 271-44-3 benzimidazole 
• 591-50-4 iodobenzene 
• 7788-69-4 1-phenyl-1H-indazole 
• 1507400-93-2 N-(2-bromophenyl)-N-phenylcyanamide 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 622-34-4 1-phenylcyanamide 

Downstream Products

• 91-40-7 2-(phenylamino)benzoic acid 
• 1002104-03-1 4-(acridin-9-yl)benzaldehyde 

Relevant articles and documents

Substituted conformationally restricted guanidine derivatives: Probing the α2-adrenoceptors’ binding pocket

In this paper we report the design, synthesis and pharmacological evaluation of new N-substituted 2-amino-1,4-dihydroquinazolines, 2-amino-1,4-dihydropyridopyrimidines and 2-amino-4,5-dihydro-1,3-benzodiazepines as α2-adrenoceptors ligands. Computational studies show that the proposed substitutions and guanidine-containing ring size will probe an extensive area of the active site. Preparation of these molecules involved novel routes than those previously utilised in our laboratory for the preparation of the acyclic aryl-guanidine counterparts. Compounds 8b and 18c showed the highest affinity and antagonistic activity, within their series, towards the α2-adrenoceptor in human brain tissue in?vitro experiments. Structure-activity relationships have been established for the design and biological evaluation of novel α2-adrenoceptor ligands.

CuSO4-Catalyzed dual annulation to synthesize O, S or N-containing tetracyclic heteroacenes

In this work, CuSO4 is utilized as a practical redox catalyst for tandem dual annulation in the synthesis of indole-fused tetracyclic heteroacenes, which are important skeletons in both medicinal chemistry and materials chemistry. The preparation of such skeletons in a convenient and efficient manner is in high demand. This method realizes the modular synthesis of benzofuro-, benzothieno-, and indoloindoles from abundant feedstocks such as 2-halobenzyl halides and nitrile derivatives in up to 99% yields, providing a rapid access to diverse indole-fused heteroacenes with biological or optoelectronic properties.

COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF

The present invention relates to a device for emitting light. Provided are a novel mixture capable of improving stability and longevity, an organic electronic element using the same, and an electronic device thereof. (by machine translation)