17659-27-7

Basic information

• Product Name: (S)-2,2,2-trifluoro-1-(phenyl)ethyl benzoate
• Synonyms: (S)-2,2,2-trifluoro-1-(phenyl)ethyl benzoate
• CAS NO: 17659-27-7
• Molecular Weight: 280.246
• Mol File: 17659-27-7.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (S)-2,2,2-trifluoro-1-(phenyl)ethyl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2,2,2-trifluoro-1-(phenyl)ethyl benzoate(17659-27-7)
• EPA Substance Registry System: (S)-2,2,2-trifluoro-1-(phenyl)ethyl benzoate(17659-27-7)

Safety Data

• Hazardous Substances Data: 17659-27-7(Hazardous Substances Data)

Upstream product

• 93-99-2 benzoic acid phenyl ester 
• 340-04-5 1-phenyl-2,2,2-trifluoromethylethanol 
• 884-09-3 phenyl thiobenzoate 
• 17659-27-7 1-benzoyloxy-1-phenyl-2,2,2-trifluoroethane 
• 93-97-0 benzoic acid anhydride 
• 13652-07-8 phenyltrifluorodiazoethane 
• 65-85-0 benzoic acid 
• 434-45-7 2,2,2-Trifluoroacetophenone 
• 100-52-7 benzaldehyde 
• 108-98-5 thiophenol 
• 49543-63-7 4-tert-butylbenzyl mercaptan 
• 66-99-9 β-naphthaldehyde 
• 98-88-4 benzoyl chloride 
• 185424-21-9 Methanesulfonic acid 2,2,2-trifluoro-1-phenyl-ethyl ester 

Downstream Products

• 340-06-7 S(+)-1-phenyl-2,2,2-trifluoroethanol 

Relevant articles and documents

Functional group transformation of α-trifluoromethylated alcohol derivatives

Functional group transformation of α-trifluoromethylated alcohols was investigated. Nucleophilic substitutions of their sulfonates was achieved in the presence of metal fluoride as a base with complete inversion of the configuration.

Synthesis, characterization and catalytic performances of benzimidazolin-2-iminato actinide (IV) complexes in the Tishchenko reactions for symmetrical and unsymmetrical esters

A new family of benzimdazolin-2-iminato actinide?(IV) complexes [(Bim7-MeDipp/MeN)An(N(SiMe3)2)3] (An = U (3), Th (4)) and [(Bim4-MeDipp/MeN)An(N(SiMe3)2)3] (An = U (5), Th (6)) were synthesized and their solid state structures were established by single-crystal X-ray diffraction analysis. The catalytic performances of complexes 3–6 towards the homo- and cross-coupling of aldehydes (Tishchenko reaction) were studied and the thorium complexes 4 and 6 displayed moderate to high activities for the production of the corresponding symmetric and unsymmetrical esters. Coupling of aldehyde and alcohols, known as the tandem proton-transfer esterification, and the intermolecular coupling reaction between aldehyde and trifluoromethylketones were also investigated by these thorium complexes, indicating a complementary method to obtain unsymmetrical esters selectively. Plausible mechanisms for these reactions are proposed based on stoichiometric studies.

Microwave-assisted efficient thiolate-catalysed homo- and crossed intermolecular Tishchenko reactions

Recently, the first efficient intermolecular crossed Tishchenko reactions were reported. The utility of these processes is curtailed by long reaction times of up to 4 days (at reflux). Herein we report that these reactions are highly susceptible to acceleration by microwave irradiation-allowing fast, efficient, high-yielding coupling to proceed in 10-180 min.