178381-05-0

Basic information

• Product Name: 4,4,5,5,6,6,6-Heptafluoro-3-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid ethyl ester
• Synonyms: 4,4,5,5,6,6,6-Heptafluoro-3-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid ethyl ester
• CAS NO: 178381-05-0
• Molecular Weight: 373.27
• Mol File: 178381-05-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4,4,5,5,6,6,6-Heptafluoro-3-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,5,5,6,6,6-Heptafluoro-3-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid ethyl ester(178381-05-0)
• EPA Substance Registry System: 4,4,5,5,6,6,6-Heptafluoro-3-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid ethyl ester(178381-05-0)

Safety Data

• Hazardous Substances Data: 178381-05-0(Hazardous Substances Data)

Upstream product

• 336-62-9 (2,2,3,3,4,4,4-heptafluorobutanoyl)acetic acid ethyl ester 
• 100-46-9 benzylamine 
• 150618-24-9 Ethyl (Z)-4,4,5,5,6,6,6-heptafluoro-3-benzylamino-2-hexenoate 

Relevant articles and documents

Catalytic asymmetric synthesis of β-fluoroalkyl-β-amino acids via biomimetic [1,3]-proton shift reaction

[1,3]-Proton shift reaction of N-benzylenamines 1a-e, derived from β- polyfluoroalkyl-β-ketocarboxylic esters and benzylamine, was catalyzed by (- )-cinchonidine (5-13 mol %) to give good yields (67-89%) of enantiomerically enriched (up to 36% ee) N-benzy