178445-27-7

Basic information

• Product Name: 2H-Isoindole-2-carboxylic acid, 5-bromo-1,3-dihydro-, phenylmethyl ester
• CAS NO: 178445-27-7
• Molecular Formula: C16H14BrNO2
• Molecular Weight: 332.197
• Mol File: 178445-27-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2H-Isoindole-2-carboxylic acid, 5-bromo-1,3-dihydro-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Isoindole-2-carboxylic acid, 5-bromo-1,3-dihydro-, phenylmethyl ester(178445-27-7)
• EPA Substance Registry System: 2H-Isoindole-2-carboxylic acid, 5-bromo-1,3-dihydro-, phenylmethyl ester(178445-27-7)

Safety Data

• Hazardous Substances Data: 178445-27-7(Hazardous Substances Data)

Upstream product

• 110-54-3 hexane 
• 501-53-1 benzyl chloroformate 
• 919346-89-7 5-bromo-2,3-dihydro-1H-isoindole hydrochloride 
• 127168-84-7 5-bromoisoindoline 
• 127168-85-8 2-(p-toluenesulfonyl)-5-bromoisoindoline 
• 69189-19-1 4-bromo-1,2-bis-bromomethyl-benzene 
• 583-71-1 4-bromo-o-xylene 

Downstream Products

• 1618083-57-0 benzyl 5-(2,3-dihydroxypropyl)isoindoline-2-carboxylate 
• 1618083-58-1 benzyl 5-(2-oxoethyl)isoindoline-2-carboxylate 
• 1618083-59-2 2-(2-benzyloxycarbonylisoindolin-5-yl)acetic acid 
• 1618083-60-5 tert-butyl 3-((2R)-2-((2-benzyloxycarbonylisoindolin-5-yl)acetamido)-2-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0^2,6]dec-4-yl)ethyl)-2-methoxybenzoate 
• 1618083-61-6 tert-butyl 3-((2R)-2-((isoindolin-5-yl)acetamido)-2-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0^2,6]dec-4-yl)ethyl)-2-methoxybenzoate 
• 1618090-65-5 tert-butyl 3-((2R)-[[2-[2-[(Z)-N,N'-bis(tert-butoxycarbonyl)carbamimidoyl]isoindolin-5-yl]acetyl]amino]-2-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0^2,6]dec-4-yl)ethyl)-2-methoxybenzoate 
• 1618083-56-9 benzyl 5-allylisoindoline-2-carboxylate 

Relevant articles and documents

NOVEL MORPHOLINYL AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE

The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

BETA-LACTAMASE INHIBITORS

Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.