178548-28-2 Usage
Chemical structure
A compound with a naphthyridine core structure and a substituted phenylmethyl group.
Application
Commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals.
Potential uses
Shown potential as an antitumor and anti-inflammatory agent, making it of interest for medicinal chemistry research.
Thermal stability
Exhibits high thermal stability, making it suitable for use in materials science applications.
Chemical nature
Aromatic and heterocyclic, making it a versatile compound for the development of new chemical entities in the field of drug discovery and materials chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 178548-28-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,5,4 and 8 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 178548-28:
(8*1)+(7*7)+(6*8)+(5*5)+(4*4)+(3*8)+(2*2)+(1*8)=182
182 % 10 = 2
So 178548-28-2 is a valid CAS Registry Number.
178548-28-2Relevant articles and documents
Synthesis of SMP-797: A new potent ACAT inhibitor
Ban, Hitoshi,Muraoka, Masami,Ohashi, Naohito
, p. 10081 - 10092 (2007/10/03)
A potent ACAT (acyl-CoA: cholesterol acyltransferase) inhibitor SMP-797 was effectively synthesized by the urea formation of 3-amino-4-aryl-1,8- naphthyridin-2(1H)-one and 4-amino-2,6-diisopropylamine. The synthesis of the former compound involved the Suzuki coupling reaction as a key step, and the latter was prepared by the 4-selective nitration of 2,6-diisopropylaniline using 2,3,5,6-tetrabromo-4-methyl-4-nitro-2,5-cyclohexadienone.
