219775-95-8 Usage
Chemical structure
A compound with a naphthyridine core structure and a hydroxy and phenylmethyl functional group.
Usage
Commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals.
Biological and pharmacological activities
Potential biological and pharmacological activities.
Anti-tumor potential
Studied for its potential as an anti-tumor agent.
Anti-inflammatory potential
Studied for its potential as an anti-inflammatory agent.
Anti-bacterial potential
Studied for its potential as an anti-bacterial agent.
Protein kinase C inhibition
Shown potential as an inhibitor of protein kinase C, an enzyme involved in various cellular processes.
Ongoing research
Under ongoing research for its potential applications in the field of medicine and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 219775-95-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,7,7 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 219775-95:
(8*2)+(7*1)+(6*9)+(5*7)+(4*7)+(3*5)+(2*9)+(1*5)=178
178 % 10 = 8
So 219775-95-8 is a valid CAS Registry Number.
219775-95-8Relevant articles and documents
Asymmetric synthesis of tetrahydropyran[3,2-c]quinolinones via an organocatalyzed formal [3 + 3] annulation of quinolinones and MBH 2-naphthoates of nitroolefin
Li, Jian,Hu, Qi-Long,Chen, Xue-Ping,Hou, Ke-Qiang,Chan, Albert S.C.,Xiong, Xiao-Feng
, p. 697 - 700 (2019/09/30)
An efficient asymmetric and enantio-swithchable organocatalytic [3 + 3] annulation reaction using MBH-2-naphthoates of nitroalkenes and 4-hydroxyquinolin-2(1H)-ones has been developed. Densely substituted tetrahydropyrano[3,2-c]quinolinones scaffolds with two adjacent stereogenic centers are obtained with high yield (up to 95% yield) and good stereoselectivities (up to >20:1 dr and 96% ee) in an enantio-switchable manner. Furthermore, gram scale synthesis was achieved and the nitro group could easily transform into an amino group without any appreciable loss in the diastereo- and enantioselectivity.
NAPHTHYRIDINE DERIVATIVE
-
Page 8, (2008/06/13)
The present invention provides a novel naphthyridine derivative that is effective for relieving pain, less toxic, and also is effective for treating diabetic neuropathy, the derivative being represented by the general formula (1) : wherein R1,