17879-35-5

Basic information

• Product Name: [(1S,3S)-3-acetyl-2,2-dimethylcyclobutyl]acetic acid
• CAS NO: 17879-35-5
• Molecular Formula: C₁₀H₁₆O₃
• Molecular Weight: 184.2322
• Mol File: 17879-35-5.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 305.2°C at 760 mmHg
• Flash Point: 152.6°C
• Density: 1.065g/cm³
• Vapor Pressure: 0.00019mmHg at 25°C
• Refractive Index: 1.465
• CAS DataBase Reference: [(1S,3S)-3-acetyl-2,2-dimethylcyclobutyl]acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [(1S,3S)-3-acetyl-2,2-dimethylcyclobutyl]acetic acid(17879-35-5)
• EPA Substance Registry System: [(1S,3S)-3-acetyl-2,2-dimethylcyclobutyl]acetic acid(17879-35-5)

Safety Data

• Hazardous Substances Data: 17879-35-5(Hazardous Substances Data)

Usage

Description

[(1S,3S)-3-acetyl-2,2-dimethylcyclobutyl]acetic acid, also known as (1S,3S)-3-acetyl-2,2-dimethylcyclobutane-1-acetic acid, is a complex organic compound characterized by a 2,2-dimethylcyclobutyl ring and an acetic acid functional group. This unique structure endows the compound with distinct structural and chemical properties, making it a promising candidate for pharmaceutical applications.

Uses

Used in Pharmaceutical Industry:
[(1S,3S)-3-acetyl-2,2-dimethylcyclobutyl]acetic acid is used as a potential component in the development of anti-inflammatory drugs due to its unique structural properties and the presence of the 2,2-dimethylcyclobutyl group. [(1S,3S)-3-acetyl-2,2-dimethylcyclobutyl]acetic acid's potential to alleviate inflammation and associated conditions is currently under investigation, with further research required to fully understand its uses and effects.
Used in Chemical Research:
In addition to its pharmaceutical applications, [(1S,3S)-3-acetyl-2,2-dimethylcyclobutyl]acetic acid is also utilized in chemical research for studying the properties and reactions of complex organic compounds with cyclobutyl rings and acetic acid functional groups. This research can contribute to the advancement of synthetic chemistry and the development of new compounds with various applications.

Upstream product

• 7785-26-4 (-)-α-pinene 
• 74281-22-4 2-((1R,3R)-3-acetyl-2,2-dimethylcyclobutyl)acetaldehyde 
• 80-56-8 Pinene 
• 67-63-0 isopropyl alcohol 
• 64396-97-0 (+)-cis-pinonic acid 
• 127-91-3 (1R,5R)-(+)-β-pinene 
• 18358-53-7 pinocamphone 
• 7785-70-8 (+)-α-pinene 
• 17879-35-5 cis-pinonic acid 
• 473-72-3 trans-(2,2-dimethyl-3-acetylcyclobutyl)acetic acid 
• 80-56-8 rac-α-pinene 
• 74281-23-5 1-((1R,3R)-3-(2,2-dimethoxyethyl)-2,2-dimethylcyclobutyl)ethan-1-one 
• 936-02-7 2-Hydroxybenzoylhydrazine 
• 54-85-3 isoniazid 

Downstream Products

• 21660-24-2 ((1S)-2.2-dimethyl-3t-acetohydroximoyl-cyclobutyl-(r))-acetic acid 
• 4426-02-2 2,2-dimethyl-3-ethylcyclobutaneacetic acid 
• 2302-79-6 (+/-)-(3c-amino-2,2-dimethyl-cyclobut-r-yl)-acetic acid 
• 473-72-3 trans-(2,2-dimethyl-3-acetylcyclobutyl)acetic acid 
• 21660-24-2 (+/-)-[3c-(1-hydroxyimino-ethyl)-2,2-dimethyl-cyclobut-r-yl]-acetic acid 
• 17879-35-5 cis-pinonic acid 
• 21660-24-2 (+/-)-(2.2-dimethyl-3t-acetohydroximoyl-cyclobutyl-(r))-acetic acid 
• 4436-81-1 homoterpenylmethylketone 
• 288848-36-2 (1'R,3'R)-2-(3'-formyl-2',2'-dimethylcyclobutyl)acetaldehyde 
• 288848-37-3 (1R,3R)-3-(2'-benzyloxyethyl)-2,2-dimethylcyclobutanocarbaldehyde 
• 288848-32-8 (1R,3R)-3-(2'-benzyloxyethyl)-2,2-dimethylcyclobutylmethanol 
• 288848-27-1 methyl (1R,3R)-3-(2'-benzyloxyethyl)-2,2-dimethylcyclobutanecarboxylate 
• 288848-35-1 (1R,3R)-3-(2'-benzyloxyethyl)-2,2-dimethylcyclobutyl methyl ketone 
• 288848-25-9 (1R,3R)-3-(2'-benzyloxyethyl)-2,2-dimethylcyclobutanecarboxylic acid 

Relevant articles and documents

Molecular Chirality and Cloud Activation Potentials of Dimeric α-Pinene Oxidation Products

The surface activity of ten atmospherically relevant α-pinene-derived dimers having varying terminal functional groups and backbone stereochemistry is reported. We find ～10% differences in surface activity between diastereomers of the same dimer, demonstrating that surface activity depends upon backbone stereochemistry. Octanol-water (KOW) and octanol-ammonium sulfate partitioning coefficient (KOAS) measurements of our standards align well with the surface activity measurements, with the more surface-active dimers exhibiting increased hydrophobicity. Our findings establish a link between molecular chirality and cloud activation potential of secondary organic aerosol particles. Given the diurnal variations in enantiomeric excess of biogenic emissions, possible contributions of such a link to biosphere:atmosphere feedbacks as well as aerosol particle viscosity and phase separation are discussed.

Transformations of Peroxide Ozonolysis Products of (–)-α-Pinene and (+)-3-Carene by the Action of 4-Hydroxybenzohydrazide

Abstract: Treatment of peroxide ozonolysis products of the bicyclic monoterpenes (–)-α-pinene and (+)-3-carene with 4-hydroxybenzohydrazide in methylene chloride or tetrahydrofuran gave the corresponding keto acids, whereas keto esters were formed in methanol.

Transformations of (-)-α-pinene peroxide ozonolysis products by hydrazines of HCL and H2SO4

The reactivities of hydrazines of HCl and H2SO4 for (-)-α-pinene peroxide ozonolysis products were studied. It was shown that these reagents were less effective and selective than semicarbazide hydrochloride for transformations into cis-pinonic acid and its esters.