178928-70-6

Basic information

• Product Name: PROTHIOCONAZOLE
• Synonyms: 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione;Prothioconazole PESTANAL;3H-1,2,4-Triazole-3-thione, 2-2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl-1,2-dihydro-;jau 6476;prothioconazole (bsi, pa iso);2-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazole-3(2H)-thione;2-[2-(1-Chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxy-propyl]-1,2-dihydro-3H-1,2,4-Triazol-3-thione
• CAS NO: 178928-70-6
• Molecular Formula: C₁₄H₁₅Cl₂N₃OS
• Molecular Weight: 344.2594
• Mol File: 178928-70-6.mol
• Article Data: 16

Chemical Properties

• Melting Point: 139.1-144.5°
• Boiling Point: 486.7 °C at 760 mmHg
• Flash Point: 248.2 °C
• Appearance: UN3077 9/PG 3
• Density: 1.5 g/cm³
• Vapor Pressure: 2.75E-10mmHg at 25°C
• Refractive Index: 1.697
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 6.9(at 25℃)
• CAS DataBase Reference: PROTHIOCONAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: PROTHIOCONAZOLE(178928-70-6)
• EPA Substance Registry System: PROTHIOCONAZOLE(178928-70-6)

Safety Data

• Hazard Codes: Xi,N
• Statements: 51/53
• Safety Statements: 61
• RIDADR: UN3077 9/PG 3
• WGK Germany: 2
• Hazardous Substances Data: 178928-70-6(Hazardous Substances Data)

Usage

Uses

Prothioconazole is an antifungal metabolite used in agricultural fungicides and herbicides.

InChI:InChI=1/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)

Upstream product

• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 
• 2444-36-2 2'-chloro-benzeneacetic acid 
• 51512-09-5 2-(2-chlorophenyl)acetyl chloride 
• 946402-82-0 2-(2-chlorophenyl)-N-methoxy-N-methylacetamide 
• 139297-65-7 1-(1-chlorocyclopropyl)-2-(2-chlorophenyl)ethanone 
• 540-72-7 sodium thiocyanide 
• 222408-91-5 [2-(1-chloro-cycloprop-1-yl)-3-(2-chlorophenyl)-2-hydroxy]-propyl-1-hydrazine 
• 298-12-4 Glyoxilic acid 
• 1147550-11-5 ammonium thiocyanate 
• 222408-90-4 [2-(1-chlorocyclopropyl-1-yl)-1-(2-chlorophenyl)-2-hydroxy-3-propane]-(1,2,4-triazolidine-3-thiol-1-yl) 
• 7783-06-4 hydrogen sulfide 
• 872-50-4 1-methyl-pyrrolidin-2-one 

Downstream Products

• 199391-98-5 di-{1-[2-(1-chlorocyclopropyl)-3-(2-chloro-phenyl)-2-hydroxy-propyl-1]-1,2,4-triazol-5-yl} disulphide 
• 199105-36-7 sodium salt of 2-(1-chloro-cyclopropyl)-1-(2-chlorophenyl)-3-(5-mercapto-1,2,4-triazol-1-yl)-propan-2-ol 
• 199851-46-2 2-(1-chloro-cyclopropyl)-1-(2-chloro-phenyl)-3-(4-methanesulphonyl-5-thiono-4,5-dihydro-1,2,4-triazol-1-yl)-propan-2-ol 
• 199110-67-3 2-(1-chloro-cyclopropyl)-1(2-chlorophenyl)-3-[5-(4-chloro-benzoyl-mercapto)-1,2,4-triazol-1-yl]-propan-2-ol 

Relevant articles and documents

AN INDUSTRIAL SCALE PROCESS FOR THE PREPARATION OF PROTHIOCONAZOLE

The present invention relates to an industrial scale process for the preparation of Prothioconazole (I), which is simple, economical, efficient, user and environment friendly, moreover commercially viable with higher yield and greater chemical purity.

IMPROVED PROCESS FOR PREPARATION OF INTERMEDIATES

PCT00760 20 ABSTRACT Disclosed herein is a process for preparation of 1-chloro-2-(1- chlorocyclopropyl)-3-(2-chlorophenyl)propan-2-ol (compound of formula (I)) 5 and 2-(1-chlorocyclopropyl)-2-[(2-chlorophenyl)methyl]oxirane (compound of formula (II)).