1791-13-5 Usage
Description
H-ASP(OTBU)-OTBU HCL, also known as L-Aspartic acid di-tert-butyl ester hydrochloride, is a white powder chemical compound. It is structurally similar to L-Glutamic acid di-tert-butyl ester and is used in various applications across different industries.
Uses
Used in Pharmaceutical Industry:
H-ASP(OTBU)-OTBU HCL is used as a research compound for neurological comparison studies with structurally similar compounds such as L-Glutamic acid di-tert-butyl ester. This helps in understanding the differences in their effects on the nervous system and developing potential therapeutic agents.
Used in Chemical Synthesis:
H-ASP(OTBU)-OTBU HCL can be used as a building block or intermediate in the synthesis of various organic compounds and pharmaceuticals. Its unique structure allows for the formation of new chemical entities with potential applications in different fields.
Used in Analytical Chemistry:
As a white powder, H-ASP(OTBU)-OTBU HCL can be used as a reference material or standard in analytical chemistry for the development and validation of analytical methods, such as chromatography, spectroscopy, and titration.
Used in Material Science:
The unique chemical properties of H-ASP(OTBU)-OTBU HCL can be utilized in the development of new materials with specific properties, such as polymers, coatings, or adhesives, depending on the desired application and industry requirements.
Biochem/physiol Actions
L-Aspartic acid di-tert-butyl ester hydrochloride may be used in neurological comparison studies with structurally similar compounds such as L-Glutamic acid di-tert-butyl ester (G7501).
Check Digit Verification of cas no
The CAS Registry Mumber 1791-13-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,9 and 1 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1791-13:
(6*1)+(5*7)+(4*9)+(3*1)+(2*1)+(1*3)=85
85 % 10 = 5
So 1791-13-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H23NO4.ClH/c1-11(2,3)16-9(14)7-8(13)10(15)17-12(4,5)6;/h8H,7,13H2,1-6H3;1H/t8-;/m0./s1
1791-13-5Relevant articles and documents
Synthesis and anticancer properties of RGD peptides conjugated to nitric oxide releasing functional groups and abiraterone
Nortcliffe, Andrew,Fleming, Ian N.,Botting, Nigel P.,O'Hagan, David
supporting information, p. 8343 - 8347 (2015/03/05)
A series of analogues of the integrin binding aspartic acid-glycine-arginine (RGD) peptide sequence were synthesised conjugated to nitric oxide (NO) donating functional groups. Also the cytotoxicity of abiraterone, a prostate cancer drug, was explored when it was conjugated in three part constructs to RGD sequences and NO releasing heterocycles. In general the analogues showed integrin binding affinity comparable to RGD reference compounds, and all released NO by the Griess test assay. Two analogues exhibited significant cytotoxic effects against PC3 and MCF7 cell lines.