438246-17-4

Basic information

• Product Name: C₁₉H₂₆N₂O₈
• Synonyms: C₁₉H₂₆N₂O₈
• CAS NO: 438246-17-4
• Molecular Weight: 410.424
• Mol File: 438246-17-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₉H₂₆N₂O₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₂₆N₂O₈(438246-17-4)
• EPA Substance Registry System: C₁₉H₂₆N₂O₈(438246-17-4)

Safety Data

• Hazardous Substances Data: 438246-17-4(Hazardous Substances Data)

Upstream product

• 13795-73-8 L-aspartic acid di-tert-butyl ester 
• 7693-46-1 4-Nitrophenyl chloroformate 
• 5070-13-3 bis-(p-nitrophenyl) carbonate 
• 1791-13-5 L-aspartic acid di-tert-butyl ester hydrochloride 

Downstream Products

• 1138406-14-0 4'-O-[CO-Asp(OtBu)-OtBu]-quercetin 
• 1138406-43-5 3'-O-[CO-Ala(OtBu)-OtBu]-quercetin 
• 1270004-52-8 4'-O-CO-[Asp(OtBu)-OtBu]-tricin 

Relevant articles and documents

METHOD OF MODULATING TIGIT AND PD-1 SIGNALLING PATHWAYS USING 1,2,4-OXADIAZOLE COMPOUNDS

The present invention relates to method of modulating TIGIT signaling pathway and PD-1 signaling pathway. The invention also encompasses the use of the compound of formula (I) or a stereoisomer thereof or a pharmaceutically acceptable salt thereof for the treatment of diseases or disorders mediated by both TIGIT signaling pathway and PD-1 signaling pathway.

In vitro solubility, stability and permeability of novel quercetin-amino acid conjugates

In order to discover a quercetin prodrug with improved bioavailability, we synthesized nine quercetin-amion acid conjugates and estimated their pharmacokinetic properties including water solubility, stability against chemical or enzymatic hydrolysis, and