17938-20-4Relevant articles and documents
Insights into the metalation of benzene and toluene by schlosser's base: A superbasic cluster comprising PhK, PhLi, and tBuOLi
Unkelbach, Christian,O'Shea, Donal F.,Strohmann, Carsten
, p. 553 - 556 (2014)
The metalation of benzene by Schlosser's base (nBuLi/tBuOK) occurs smoothly in THF at low temperatures to afford a discrete mixed-metal Li 2K4 cluster that contains phenyl anions and tert-butoxide. The aggregate itself exhibits superbasic behavior by metalating toluene. The delocalized benzyl anion obtained this way πbonds to potassium counterions, thereby creating a 2D coordination polymer. A discrete mixed-metal Li 2K4 cluster that contains phenyl anions and tert-butoxide is formed smoothly by the metalation of benzene by Schlosser's base (nBuLi/tBuOK) in THF at low temperatures (see picture). The aggregate itself exhibits superbasic behavior by metalating toluene. The delocalized benzyl anion obtained this way πbonds to potassium counterions, thereby creating a 2D coordination polymer.
Tertiary α-Silyl Alcohols by Diastereoselective Coupling of 1,3-Dienes and Acylsilanes Initiated by Enantioselective Copper-Catalyzed Borylation
Feng, Jian-Jun,Oestreich, Martin
supporting information, p. 8211 - 8215 (2019/05/27)
An efficient synthesis of functionalized tertiary α-silyl alcohols by an enantio- and diastereoselective copper-catalyzed three-component coupling of 1,3-dienes, bis(pinacolato)diboron, and acylsilanes is reported. The reaction proceeds well with different 1,3-dienes and a broad range of aryl- as well as alkenyl- but also alkyl-substituted acylsilanes. The target compounds are formed with high regio-, diastereo-, and enantioselectivity (up to 99 % ee and d.r. >20:1) and are highly versatile synthetic building blocks.
Palladium-catalyzed silylation reaction between benzylic halides and silylboronate
Huang, Zhi-Dao,Ding, Ran,Wang, Peng,Xu, Yun-He,Loh, Teck-Peng
supporting information, p. 5609 - 5612 (2016/05/09)
An efficient Pd-catalyzed silylation reaction of benzylic halides with silylboronate is reported. In this reaction, primary and secondary benzylic halides could react well with silylboronates to afford benzylic silanes. This reaction accommodates a broad substrate scope and proceeds smoothly under very mild reaction conditions. The corresponding products could be obtained in moderate to high yields and with stereospecificity.
