17960-37-1

Basic information

• Product Name: 4-(2-FURYL)-4-OXOBUTANENITRILE
• Synonyms: 4-(furan-2-yl)-4-oxobutanenitrile
• CAS NO: 17960-37-1
• Molecular Formula: C₈H₇NO₂
• Molecular Weight: 0
• Mol File: 17960-37-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 325.5°Cat760mmHg
• Flash Point: 150.7°C
• Appearance: /
• Density: 1.145g/cm³
• Vapor Pressure: 0.000229mmHg at 25°C
• Refractive Index: 1.491
• CAS DataBase Reference: 4-(2-FURYL)-4-OXOBUTANENITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-FURYL)-4-OXOBUTANENITRILE(17960-37-1)
• EPA Substance Registry System: 4-(2-FURYL)-4-OXOBUTANENITRILE(17960-37-1)

Safety Data

• Hazardous Substances Data: 17960-37-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H7NO2/c9-5-1-3-7(10)8-4-2-6-11-8/h2,4,6H,1,3H2

Upstream product

• 151-50-8 potassium cyanide 
• 41220-23-9 3-(2-furyl)-N,N-dimethyl-3-oxo-1-propanamine hydrochloride 
• 98-01-1 furfural 
• 64-17-5 ethanol 
• 107-13-1 acrylonitrile 
• 107-14-2 chloroacetonitrile 
• 111886-29-4 tert-butyldimethyl((1-(furan-2-yl)vinyl)oxy)silane 
• 88-14-2 2-furanoic acid 
• 81331-50-2 S-(2-pyridinyl) furan-2-carbothioate 

Downstream Products

• 104704-31-6 5-[2]furyl-3,4-dihydro-2H-pyrrole 
• 92850-93-6 1-benzoyl-2-furan-2-yl-pyrrolidine 
• 90086-89-8 2-(furan-2-yl)pyrrolidine 
• 37757-45-2 4-oxosuberic acid 

Relevant articles and documents

A Photochemical Organocatalytic Strategy for the α-Alkylation of Ketones by using Radicals

Reported herein is a visible-light-mediated radical approach to the α-alkylation of ketones. This method exploits the ability of a nucleophilic organocatalyst to generate radicals upon SN2-based activation of alkyl halides and blue light irradiation. The resulting open-shell intermediates are then intercepted by weakly nucleophilic silyl enol ethers, which would be unable to directly attack the alkyl halides through a traditional two-electron path. The mild reaction conditions allowed functionalization of the α position of ketones with functional groups that are not compatible with classical anionic strategies. In addition, the redox-neutral nature of this process makes it compatible with a cinchona-based primary amine catalyst, which was used to develop a rare example of enantioselective organocatalytic radical α-alkylation of ketones.

Synthesis of thermoregulated phase-separable triazolium ionic liquids catalysts and application for Stetter reaction

A series of polyether-substituted triazolium ionic liquids catalysts have been first synthesized for resolving the problem of separation and reuse of Stetter catalysts. The catalysts possess the properties of critical solution temperature (CST) and inverse temperature-dependent solubility in toluene/heptane solvents. Based on these properties, the catalysts can achieve the catalytic process named as thermoregulated phase-separable catalysis (TPSC) with the characteristic of homogeneous reaction at higher temperature and phase-separation at lower temperature. The novel TPSC system has been successfully applied for Stetter reaction of furfural or butanal with ethyl acrylate. The experimental results have showed that the novel catalysts exhibit excellent TPSC with high recycling efficiency.

OMEGA-HETEROAROYL(PROPIONYL OR BUTYRYL)-L-PROLINES

This disclosure describes novel substituted ω-heteroaroyl(propionyl or butyryl)-L-prolines and the esters and cationic salts thereof which are useful as hypotensive agents in mammals.