90086-89-8

Basic information

• Product Name: 2-(Furan-2-yl)pyrrolidine
• Synonyms: 2-(2-FURYL)-PYRROLIDINE;2-FURAN-2-YL-PYRROLIDINE;2-(FURAN-2-YL)PYRROLIDINE, 98+%;2-(Fur-2-yl)pyrrolidine;2-Furan-2-yl-pyrrolidine hydrochoride;2-(2-furyl)pyrrolidine(SALTDATA: HCl);2-(Pyrrolidin-2-yl)furan
• CAS NO: 90086-89-8
• Molecular Formula: C₈H₁₁NO
• Molecular Weight: 137.18
• Product Categories: Benzenes
• Mol File: 90086-89-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 207.9 °C at 760 mmHg
• Flash Point: 79.5 °C
• Appearance: /
• Density: 1.041g/cm³
• Vapor Pressure: 0.22mmHg at 25°C
• Refractive Index: 1.496
• PKA: 10.13±0.10(Predicted)
• CAS DataBase Reference: 2-(Furan-2-yl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Furan-2-yl)pyrrolidine(90086-89-8)
• EPA Substance Registry System: 2-(Furan-2-yl)pyrrolidine(90086-89-8)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 90086-89-8(Hazardous Substances Data)

Usage

General Description

2-(Furan-2-yl)pyrrolidine is a heterocyclic compound that consists of a pyrrolidine ring with a furan ring attached to one of its nitrogen atoms. It is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. The presence of the furan and pyrrolidine rings imparts unique properties to the molecule, making it useful in the creation of various functional materials. 2-(Furan-2-yl)pyrrolidine has also shown potential as a ligand in metal-catalyzed reactions, and it exhibits interesting biological activities that make it an attractive target for drug discovery and development. Overall, 2-(Furan-2-yl)pyrrolidine is a versatile and valuable chemical building block with a wide range of potential applications in the fields of chemistry, pharmaceuticals, and materials science.

InChI:InChI=1/C8H11NO/c1-3-7(9-5-1)8-4-2-6-10-8/h2,4,6-7,9H,1,3,5H2

Upstream product

• 502546-17-0 5-(2-furanyl)-1-pyrroline 
• 5724-81-2 1-pyrroline 
• 110-00-9 furan 
• 17960-37-1 4-(furan-2-yl)-4-oxobutanenitrile 
• 138084-62-5 2,2,5,5-tetrametyl-1-aza-2,5-disilacyclopentane-1-propyl magnesium bromide 
• 95091-92-2 N-methoxy-N-methyl-2-furancarboxamide 

Downstream Products

• 849623-03-6 3'-[(2-amino-2-benzyl-3-hydroxypropoxy)methyl]-5'-{[2-(2-furyl)pyrrolidin-1-yl]carbonyl}-1,1'-biphenyl-2-carbonitrile 

Relevant articles and documents

α-Functionalization of Cyclic Secondary Amines: Lewis Acid Promoted Addition of Organometallics to Transient Imines

Cyclic imines, generated in situ from their corresponding N-lithiated amines and a ketone hydride acceptor, undergo reactions with a range of organometallic nucleophiles to generate α-functionalized amines in a single operation. Activation of the transient imines by Lewis acids that are compatible with the presence of lithium alkoxides was found to be crucial to accommodate a broad range of nucleophiles including lithium acetylides, Grignard reagents, and aryllithiums with attenuated reactivities.