179690-96-1

Basic information

• Product Name: methyl 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]butanoate
• Synonyms: methyl 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]butanoate
• CAS NO: 179690-96-1
• Molecular Weight: 356.537
• Mol File: 179690-96-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]butanoate(179690-96-1)
• EPA Substance Registry System: methyl 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]butanoate(179690-96-1)

Safety Data

• Hazardous Substances Data: 179690-96-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 118715-16-5 4-((tert-butyldiphenylsilyl)oxy)butanoic acid 
• 925-57-5 methyl 4-hydroxybutanoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 768401-65-6 tert-butyl (1S,3R,5S,7S)-3-(tert-butyl)-7-chloro-7-[2-(tert-butyldiphenylsilyloxy)ethyl]-2-oxa-6-oxo-4-azabicyclo[3.2.0]heptane-4-carboxylate 
• 768401-64-5 methyl (1S,3R,5R,7R)-3-(tert-butyl)-7-chloro-6-oxo-7-(2-tert-butyldiphenylsilyloxy)ethyl-2-oxa-4-azabicyclo[3.2.0]heptane-4-carboxylate 
• 768401-44-1 2-chloro-4-tert-butyldiphenylsilyloxybutanoyl chloride 
• 768401-41-8 2-chloro-4-tert-butyldiphenylsilyloxybutanoic acid 
• 768401-38-3 methyl 2-chloro-4-tert-butyldiphenylsilyloxybutanoate 
• 322391-59-3 β-ketoester (36) 
• 904681-25-0 5-(t-butyldiphenylsilyloxy)-2-methylpentan-2-ol 

Relevant articles and documents

Model studies related to CP-225,917: Stereocontrolled generation of the quaternary center

The enolate derived from ester 15 reacts with diketone 10 stereoselectively (10:1), and the major isomer can be converted into lactone 21. This rearranges in boiling 1,2-dichlorobenzene to afford the tricyclic lactone 22, a model compound which shares wit

Diastereoselective synthesis of the C17-C30 fragment of amphidinol 3

The diastereoselective synthesis of the C17-C30 fragment of amphidinol 3 (AM3) 1 was achieved from the enantio-enriched aldehyde 20, Weinreb amide 14 and 2-bromo-3-(trimethylsilyl)propene, which was used as a bifunctional conjunctive reagent. The absolute configuration of the stereogenic centers, in both aldehyde 20 and Weinreb amide 14, were efficiently controlled by using (+)-(R)-methyl-p-tolylsulfoxide as the unique source of chirality.