18020-59-2

Basic information

• Product Name: 2-(HYDROXY-PHENYL-METHYL)-ACRYLIC ACID METHYL ESTER
• Synonyms: 2-(HYDROXY-PHENYL-METHYL)-ACRYLIC ACID METHYL ESTER;Methyl 2-[hydroxy(phenyl)methyl]acrylate
• CAS NO: 18020-59-2
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21118
• Mol File: 18020-59-2.mol
• Article Data: 160

Chemical Properties

• Melting Point: 126-128 °C
• Boiling Point: 322.186 °C at 760 mmHg
• Flash Point: 137.567 °C
• Appearance: /
• Density: 1.141 g/cm³
• PKA: 12.85±0.20(Predicted)
• CAS DataBase Reference: 2-(HYDROXY-PHENYL-METHYL)-ACRYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(HYDROXY-PHENYL-METHYL)-ACRYLIC ACID METHYL ESTER(18020-59-2)
• EPA Substance Registry System: 2-(HYDROXY-PHENYL-METHYL)-ACRYLIC ACID METHYL ESTER(18020-59-2)

Safety Data

• Hazardous Substances Data: 18020-59-2(Hazardous Substances Data)

Usage

General Description

2-(Hydroxy-phenyl-methyl)-acrylic acid methyl ester, also known as hydroxyphenylmethacrylic acid methyl ester, is a chemical compound with the molecular formula C10H10O3. 2-(HYDROXY-PHENYL-METHYL)-ACRYLIC ACID METHYL ESTER is an ester of hydroxyphenylmethacrylic acid, which is a derivative of acrylic acid. It is commonly used in the production of polymers and resins, as well as in the synthesis of pharmaceuticals and other organic compounds. This chemical is known for its ability to polymerize and form strong, durable materials, making it valuable in a variety of industrial and commercial applications. It is also used in the production of adhesives, coatings, and other products in the chemical and manufacturing industries.

Upstream product

• 100-52-7 benzaldehyde 
• 292638-85-8 acrylic acid methyl ester 
• 922-67-8 propynoic acid methyl ester 
• 82588-83-8 methyl 3-hydroxy-2-(nitromethyl)-3-phenylpropanoate 
• 70-55-3 toluene-4-sulfonamide 
• 98-10-2 benzenesulfonamide 
• 3144-09-0 methanesulfonamide 
• 1129-26-6 4-methoxybenzene sulfonamide 
• 5455-59-4 2-Nitrobenzenesulfonamide 
• 123-11-5 4-methoxy-benzaldehyde 
• 222179-57-9 methyl 2-methylene-3-phenyl-3-(2-tetrahydropyranyloxy)propanoate 
• 2327-99-3 1-phenylpropadiene 
• 124-38-9 carbon dioxide 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 130889-16-6 2-[(Diethoxy-phosphanyloxy)-phenyl-methyl]-acrylic acid methyl ester 
• 94199-26-5 (2S,3R)-methyl 3-hydroxy-2-methyl-3-phenylpropionate 
• 18020-59-2 methyl (S)-3-hydroxy-3-phenyl-2-methylenepropanoate 
• 147687-45-4 (+/-)-3-hydroxy-2-methylene-3-phenylpropanoic acid 
• 131469-58-4 methyl 2-benzoyloxirane-2-carboxylate 
• 124957-36-4 Methyl 3-acetoxy-2-methylene-3-phenylpropanoate 
• 76549-05-8 methyl (2R,3R)-3-hydroxy-2-methyl-3-phenylpropanoate 
• 36041-80-2 (2R,3S)-methyl 3-hydroxy-2-methyl-3-phenylpropanoate 
• 139669-41-3 (5S,6S)-2-Oxo-6-phenyl-tetrahydro-pyran-3,5-dicarboxylic acid dimethyl ester 
• 139669-41-3 (5R,6S)-2-Oxo-6-phenyl-tetrahydro-pyran-3,5-dicarboxylic acid dimethyl ester 
• 139669-29-7 anti-dimethyl 2-<(1-hydroxy)-phenylmethyl>-4-(methoxycarbonyl)-1,5-pentanedioate 
• 139669-29-7 syn-dimethyl 2-<(1-hydroxy)-phenylmethyl>-4-(methoxycarbonyl)-1,5-pentanedioate 
• 98061-70-2 6-Chloro-3-[1-phenyl-meth-(E)-ylidene]-chroman-2-one 

Relevant articles and documents

Acceleration of the Baylis-Hillman reaction in the presence of ionic liquids

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Kinetic and mechanistic investigations of the Baylis-Hillman reaction in ionic liquids

We report here a quantitative study of the kinetics and mechanism of the Baylis-Hillman reaction in the presence of ionic liquids as solvent media. Apparently, a simple Baylis-Hillman reaction can occur by two different exclusive mechanisms in ionic liquids. The delicate balance of these mechanisms is maintained by the ionic environment employed. The main features of the possible mechanism have been described here along with interesting kinetic consequences. The measurement of rate constants and activation energy parameters demonstrate that as the medium becomes basic, the order of the reaction changes from 1 to 2. An unexpected change in the mechanism of the reaction is observed with a change in the nature of the ionic liquid. The Linear Solvation Energy Relationship has also been used as an investigating tool to delineate the respective contributions of the cation and anion of the ionic liquid. The observation strongly dictates the dependency of the mechanism of the Baylis-Hillman reaction on the nature of the anion of the ionic liquids undertaken for this study.

β,γ-Diaryl α-methylene-γ-butyrolactones as potent antibacterials against methicillin-resistant Staphylococcus aureus

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