182251-94-1

Basic information

• Product Name: 2-azido-1-phenylvinyl 3-cyclopentylpropionate
• Synonyms: 2-azido-1-phenylvinyl 3-cyclopentylpropionate
• CAS NO: 182251-94-1
• Molecular Weight: 285.346
• Mol File: 182251-94-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-azido-1-phenylvinyl 3-cyclopentylpropionate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-azido-1-phenylvinyl 3-cyclopentylpropionate(182251-94-1)
• EPA Substance Registry System: 2-azido-1-phenylvinyl 3-cyclopentylpropionate(182251-94-1)

Safety Data

• Hazardous Substances Data: 182251-94-1(Hazardous Substances Data)

Upstream product

• 104-97-2 cyclopentanepropanoyl chloride 
• 1816-88-2 2-azido-1-phenylethan-1-one 

Downstream Products

• 182251-97-4 (R)-N-[4-[2-[N-(1,1-Dimethylethoxycarbonyl)-N-[2-Hydroxy-2-(Pyridin-3-Yl)Ethyl]Amino]Ethyl]Phenyl]-4-[2-(2-Cyclopentylethyl)Oxazol-5-yl]Benzenesulfonamide 
• 173902-04-0 (R)-N-[4-[2-[[2-Hydroxy-2-(pyridin-3-yl)ethyl]amino]ethyl]phenyl]-4-[2-(2-cyclopentylethyl)oxazol-5-yl]benzenesulfonamide 
• 182251-96-3 4-[2-(2-cyclopentylethyl)oxazol-5-yl]benzenesulfonyl chloride 
• 182251-95-2 2-(2-cyclopentylethyl)-5-phenyloxazole 

Relevant articles and documents

Substituted oxazole benzenesulfonamides as potent human β3 adrenergic receptor agonists

As a part of our investigation into the development of orally bioavailable β3 adrenergic receptor agonists, we have identified a series of substituted oxazole derivatives that are potent β3 agonists with excellent selectivity against other β receptors. Several of these compounds showed excellent oral bioavailability in dogs. One example, cyclopentylethyloxazole 5f is a potent β3 agonist (EC50 = 14 nM, 84% activation) with 340-fold and 160-fold selectivity over β1 and β2 receptors, respectively, and has 38% oral bioavailability in dogs. (C) 2000 Elsevier Science Ltd. All rights reserved.