18245-74-4

Basic information

• Product Name: Benzeneethanethioic acid, S-phenyl ester
• CAS NO: 18245-74-4
• Molecular Formula: C14H12OS
• Molecular Weight: 228.315
• Mol File: 18245-74-4.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Benzeneethanethioic acid, S-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanethioic acid, S-phenyl ester(18245-74-4)
• EPA Substance Registry System: Benzeneethanethioic acid, S-phenyl ester(18245-74-4)

Safety Data

• Hazardous Substances Data: 18245-74-4(Hazardous Substances Data)

Upstream product

• 930-69-8 sodium thiophenolate 
• 103-80-0 phenylacetyl chloride 
• 100693-33-2 1-cyclohexene 
• 110372-04-8 phenyl α-trimethylsilyl-1-cyclopentenylmethyl sulfide 
• 882-33-7 diphenyldisulfane 
• 100-44-7 benzyl chloride 
• 98-09-9 benzenesulfonyl chloride 
• 14040-11-0 tungsten hexacarbonyl 
• 1449477-04-6 (phenylsulfenyl)zinc bromide 
• 159971-26-3 PhSZnCl 
• 120346-64-7 (E)-3-phenyl-2-phenylsulphonyl-2-phenylthiooxirane 
• 120346-60-3 (E)-2-phenyl-1-phenylsulphonyl-1-phenylthioethene 
• 15296-86-3 1-(phenylsulfanyl)methyl phenyl sulfone 
• 35453-12-4 phenyl phenylthiomethyl sulfoxide 

Relevant articles and documents

Synthesis of Thiol Esters Using PhSZnBr as Sulfenylating Agent: A DFT-Guided Optimization of Reaction Conditions

The use of PhSZnBr as sulfenylating agent in a solvent-free protocol to prepare thiol esters in excellent yields from acyl chlorides is reported. The products were efficiently obtained by grinding the neat reagents for 5 min in a mortar. DFT calculations

Method for preparing thioester compounds through carbonylation

The invention discloses a method for preparing thioester compounds through carbonylation, wherein the method comprises the following steps: adding palladium acetate, 4,5-bis(diphenylphosphine)-9,9-dimethyl xanthene, tungsten carbonyl, triethylamine, water, a benzyl chloride compound and sulfonyl chloride into an organic solvent, collecting, reacting at the temperature of 100 DEG C for 24 hours, and after the reaction is completed, performing post-treatment to obtain the thioester compounds. The preparation method is simple to operate, the initial raw materials of the reaction are cheap and easy to obtain, sulfonyl chloride is used as a sulfur source, and a thiol compound with unpleasant smell can be prevented from being used. The substrate is high in designability, the tolerance range of functional groups of the substrate is wide, and the reaction efficiency is high. Tungsten carbonyl can be used as a carbonyl source and a reducing agent, and an additional reducing agent is not needed. Various thioester compounds can be synthesized according to actual requirements, so that the practicability of the method is widened while the operation is convenient.

An efficient synthesis of thioesters via TFA-catalyzed reaction of carboxylic acid and thiols: Remarkably facile C-S bond formation

A general, facile, and efficient new synthetic path to thioesters was established by employing defined TFA-catalyzed reaction of carboxylic acid and thiol under mild conditions. The structure of the newly synthesized compounds was determined by infrared spectroscopy, nuclear magnetic resonance, and a single crystal X-ray crystallographic analysis. Supplemental materials are available for this paper. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. Copyright