182621-52-9 Usage
General Description
TERT-BUTYL 4-ACETAMIDO-4-PHENYLPIPERIDINE-1-CARBOXYLATE is a chemical compound with the molecular formula C18H26N2O3. It is a piperidine derivative with a tert-butyl group and an acetamido group attached to the piperidine ring. TERT-BUTYL 4-ACETAMIDO-4-PHENYLPIPERIDINE-1-CARBOXYLATE is commonly used in the field of organic chemistry as a building block for the synthesis of pharmaceuticals and other complex organic molecules. It is also used as a precursor in the preparation of various chemical intermediates. Additionally, its unique structure and properties make it a valuable tool for studying the reactivity and behavior of piperidine derivatives in chemical reactions. Overall, TERT-BUTYL 4-ACETAMIDO-4-PHENYLPIPERIDINE-1-CARBOXYLATE has versatile applications in the field of organic synthesis and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 182621-52-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,6,2 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 182621-52:
(8*1)+(7*8)+(6*2)+(5*6)+(4*2)+(3*1)+(2*5)+(1*2)=129
129 % 10 = 9
So 182621-52-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H26N2O3/c1-14(21)19-18(15-8-6-5-7-9-15)10-12-20(13-11-18)16(22)23-17(2,3)4/h5-9H,10-13H2,1-4H3,(H,19,21)
182621-52-9Relevant articles and documents
A reliable and efficient synthesis of SR 142801
Giardina,Grugni, Mario,Rigolio, Roberto,Vassallo, Marco,Erhard, Karl,Farina, Carlo
, p. 2307 - 2310 (2007/10/03)
A convenient synthesis of the potent human NK-3 receptor antagonist SR 142801, (S)-(+)-N-{{3-[1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1 -yl}-4-phenylpiperidin-4-yl}-N-methylacetamide [(S)-(+)-(15)], is described. Improvements over the previously reported procedure are the preparation of the intermediate 5 via the novel imide 3 and subsequent reaction with the nucleophile 14, which reacts, regioselectively, at the endocyclic nitrogen.
