1830-68-8

Basic information

• Product Name: Benzene, 1-(1-methylethenyl)-4-nitro-
• CAS NO: 1830-68-8
• Molecular Formula: C9H9NO2
• Molecular Weight: 163.176
• Mol File: 1830-68-8.mol
• Article Data: 28

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(1-methylethenyl)-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(1-methylethenyl)-4-nitro-(1830-68-8)
• EPA Substance Registry System: Benzene, 1-(1-methylethenyl)-4-nitro-(1830-68-8)

Safety Data

• Hazardous Substances Data: 1830-68-8(Hazardous Substances Data)

Upstream product

• 1817-47-6 4-nitrocumene 
• 3276-35-5 2-nitro-2-(4-nitrophenyl)propane 
• 2492-26-4 sodium 2-mercaptobenzothiazole 
• 40107-54-8 4-methyl-3H-thiazole-2-thione; sodium salt 
• 105639-51-8 (p-nitrocumyl)quinuclidinium chloride 
• 22357-57-9 2-(4-nitrophenyl)propan-2-ol 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 100-19-6 (4-nitrophenyl)ethanone 
• 20667-19-0 methyltriphenylphosphonium iodide 
• 586-78-7 para-nitrophenyl bromide 
• 126726-62-3 2-isopropenyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 
• 1265920-51-1 N-[1-(4-nitrophenyl)ethylidene]-N'-(2,2,3-trimethylpenta-3,4-dienylidene)hydrazine 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 636-98-6 p-nitrobenzene iodide 

Downstream Products

• 14500-58-4 4-nitrocumyl chloride 
• 56077-92-0 peroxymethylene radical 
• 100-19-6 (4-nitrophenyl)ethanone 
• 301326-36-3 C₁₀H₉Br₂NO₂ 
• 1296172-71-8 2-(4-nitrophenyl)-1-phenylpropan-2-ol 
• 75590-19-1 p-nitro-α-methylstyrene oxide 
• 56858-46-9 1-(4-nitrophenyl)-2-(toluene-4-sulfonyl)ethanone 
• 22357-57-9 2-(4-nitrophenyl)propan-2-ol 
• 1962-08-9 4-(prop-1-en-2-yl)aniline 
• 69096-81-7 3-methyl-1,3-ddiphenylbutan-1-one 
• 119-61-9 benzophenone 
• 75-89-8 2,2,2-trifluoroethanol 
• 75-90-1 2,2,2-Trifluoroacetaldehyde 

Relevant articles and documents

The kinetics and mechanism of the reaction of p-nitrocumyl bromide with nitrite ions in dimethyl sulfoxide. Evidence for a non-chain reaction giving a high nitro/nitrite ratio in the product

The reaction of p-nitrocumyl bromide (RBr) with sodium nitrite in [2H6]dimethyl sulfoxide gives none of the conventional evidence for an SRN1 chain reaction but the initial values of the [RNO2]/[RONO] ratio (2.5

METHOD FOR OXIDATIVE CLEAVAGE OF COMPOUNDS WITH UNSATURATED DOUBLE BOND

A method for oxidative cleavage of a compound with an unsaturated double bond is provided. The method includes the steps of: (A) providing a compound (I) with an unsaturated double bond, a trifluoromethyl-containing reagent, and a catalyst; wherein, the catalyst is represented by Formula (II): M(O)mL1yL2z??(II);wherein, M, L1, L2, m, y, z, R1, R2 and R3 are defined in the specification; and(B) mixing the compound with an unsaturated double bond and the trifluoromethyl-containing reagent to perform an oxidative cleavage of the compound with the unsaturated double bond by using the catalyst in air or under oxygen atmosphere condition to obtain a compound represented by Formula (III):

METHOD FOR OXIDATIVE CLEAVAGE OF COMPOUNDS WITH UNSATURATED DOUBLE BOND

A method for oxidative cleavage of a compound with an unsaturated double bond is provided. The method comprises the following step: (A) providing a compound (I) with an unsaturated double bond, a reagent with trifluoromethyl, and a catalyst; wherein the catalyst is represented by the following formula (II): M(O)mL1yL2z (II); wherein, M, L1, L2, m, y, z, R1, R2 and R3 are defined in the specification; and (B) mixing the compound with an unsaturated double bond and the reagent with a trifluoromethyl to perform an oxidation of the compound with the unsaturated double bond by using the catalyst at air or an oxygen condition to get a compound presented as formula (III):

Palladium/Acid Relay Catalyzed Tandem Heck Coupling/6-Endo Cyclization between ortho-Halogenated Benzoates and Unactivated Terminal Alkenes for the Synthesis of 1-Isochromanones

We report a unique and expeditious route to synthesize 1-isochromanone derivatives through palladium catalyzed tandem Heck coupling/6-endo hydroacyloxylation cyclization between readily available ortho-halogenated benzoates and unactivated alkenes. Various 2-bromo or 2-iodo benzoates can be coupled efficiently with a broad range of alkenes to afford functionalized 1-isochromanones in high yields. Significantly, this cost-efficient and easy-to-handle synthetic methodology will have great prospect application in the synthetic and medicinal chemistry. (Figure presented.).