183253-63-6

Basic information

• Product Name: (R)-4-Benzhydryl-3-{(R)-2-[(1R,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-propyl]-octadecanoyl}-oxazolidin-2-one
• CAS NO: 183253-63-6
• Molecular Weight: 708.11
• Mol File: 183253-63-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-Benzhydryl-3-{(R)-2-[(1R,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-propyl]-octadecanoyl}-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-Benzhydryl-3-{(R)-2-[(1R,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-propyl]-octadecanoyl}-oxazolidin-2-one(183253-63-6)
• EPA Substance Registry System: (R)-4-Benzhydryl-3-{(R)-2-[(1R,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-propyl]-octadecanoyl}-oxazolidin-2-one(183253-63-6)

Safety Data

• Hazardous Substances Data: 183253-63-6(Hazardous Substances Data)

Upstream product

• 74262-56-9 (2R)-2-(tert-butyldimethylsilyloxy)propanal 
• 183116-90-7 (R)-4-Benzhydryl-3-octadecanoyl-oxazolidin-2-one 
• 173604-33-6 (4R)-4-(diphenylmethyl)-2-oxazolidinone 
• 112-76-5 Stearoyl chloride 

Relevant articles and documents

Enantiospecific synthesis of trisubstituted butyrolactone natural products and their analogs

A general methodology for the synthesis of highly substituted butyrolactones in enantiomerically pure form has been developed. The application of this process in a highly efficient synthesis of lactone natural products blastmycinone (1), NFX-2 (2), antimycinone (3), and NFX-4 (4) and two lipid metabolites (5, 6) are described. Additionally, the total synthesis of 5-epi-blastmycinone (22), 5-epi-NFX-2 (21b), 5-epi-NFX-4 (21c), and lipid metabolite analogs (19, 20) are also described. The overall yields for the target molecules are the highest reported so far in the literature.