18343-04-9Relevant articles and documents
Rare-Earth-Metal-Catalyzed Synthesis of Azaindolines and Naphthyridines via C?H Cyclization of Functionalized Pyridines
Ye, Pengqing,Shao, Yinlin,Zhang, Fangjun,Zou, Jinxuan,Ye, Xuanzeng,Chen, Jiuxi
, p. 851 - 857 (2020)
We report herein a rare-earth-metal-catalyzed insertion of a 2-pyridine C(sp2)?H bond into an intramolecular unactivated vinyl bond. This reaction provides streamlined access to a range of azaindolines in moderate to excellent yields. The salient features of this reaction include simple and mild reaction conditions, 100% atom efficiency, and wide substrate scope. This methodology is also used to construct other nitrogen-containing compounds such as naphthyridine derivatives. A plausible mechanism for the formation of azaindolines involving initial C?H bond activation by the lanthanide complex followed by C=C insertion into a Ln?C bond to form an alkyl lanthanide species that subsequently undergoes cyclization is proposed. (Figure presented.).
Hydropyridylation of Olefins by Intramolecular Minisci Reaction
Bordi, Samuele,Starr, Jeremy T.
supporting information, p. 2290 - 2293 (2017/05/12)
An unprecedented cheap, mild and easy methodology for an intramolecular Minisci reaction based on a hydrogen atom transfer (HAT) initiated hydrofunctionalization of olefins was developed. The method is suitable for the construction of unusual dihydropyrano-pyridine and 1,2,3,4-tetrahydronaphthiridine structures and, unlike most similar reactions, does not require exclusion of air from the reaction medium.
Photoreaction of 3-Allyloxy-2-pentamethyldisilanylpyridine
Kim, Myeong Shin,Park, Seung Ki
, p. 3373 - 3376 (2015/04/22)
-
