18370-11-1

Basic information

• Product Name: N-METHYL-P-TOLUAMIDE
• Synonyms: TIMTEC-BB SBB008263;N-METHYL-P-TOLUAMIDE;N,P-DIMETHYLBENZAMIDE;N,4-Dimethylbenzamide;Benzamide, N,4-dimethyl- (9CI);p-Dimethylbenzamide;N-Methyl-4-MethylbenzaMide, 97%;BenzaMide, N,4-diMethyl-
• CAS NO: 18370-11-1
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.19
• Product Categories: AMIDE
• Mol File: 18370-11-1.mol
• Article Data: 55

Chemical Properties

• Boiling Point: 293.2 °C at 760 mmHg
• Flash Point: 168.3 °C
• Appearance: /
• Density: 1.021 g/cm³
• Vapor Pressure: 0.00175mmHg at 25°C
• Refractive Index: 1.524
• CAS DataBase Reference: N-METHYL-P-TOLUAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYL-P-TOLUAMIDE(18370-11-1)
• EPA Substance Registry System: N-METHYL-P-TOLUAMIDE(18370-11-1)

Safety Data

• Hazardous Substances Data: 18370-11-1(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Canadian Journal of Chemistry, 64, p. 2010, 1986 DOI: 10.1139/v86-332

InChI:InChI=1/C9H11NO/c1-7-3-5-8(6-4-7)9(11)10-2/h3-6H,1-2H3,(H,10,11)

Upstream product

• 99-94-5 p-Toluic acid 
• 74-89-5 methylamine 
• 24400-15-5 dimethylchloronium 
• 104-85-8 para-methylbenzonitrile 
• 1613-85-0 N-methyl-N-(4-methylbenzoyl)hydroxylamine 
• 822-39-9 2-chloro-1,3,2-dioxaphospholan 
• 104-87-0 4-methyl-benzaldehyde 
• 85462-16-4 N-Methyl-O-p-nitrophenylsulphonylhydroxylamine 
• 16155-60-5 5-phenyl-2-p-tolyloxazole 
• 589-57-1 diethyl phosphorylchloridite 
• 38559-37-4 N-(p-Toluoyl)-O-(N,N-dimethylthiocarbamoyl)-N-methyl-hydroxylamin 
• 56108-06-6 p-toluimidic acid methyl ester 
• 74-88-4 methyl iodide 
• 874-60-2 4-methyl-benzoyl chloride 

Downstream Products

• 329940-36-5 N-methyl-3-nitro-4-methylbenzamide 
• 104-85-8 para-methylbenzonitrile 
• 23754-45-2 4-(Methylaminocarbonyl)benzoic acid 
• 99-75-2 4-methyl-benzoic acid methyl ester 
• 39887-40-6 4-methyl-N-n-propylbenzamide 
• 16409-28-2 N-sec-butyl-4-methylbenzamide 
• 42498-32-8 N-tert-butyl-4-methylbenzamide 
• 59746-40-6 pyrrolidin-1-yl(p-tolyl)methanone 
• 23886-71-7 4-methoxy-4'-methylbenzophenone 
• 589-18-4 4-Methylbenzyl alcohol 
• 104-87-0 4-methyl-benzaldehyde 
• 94-08-6 4-methylbenzoic acid ethyl ester 
• 530145-18-7 tert-butyl methyl(4-methylbenzoyl)carbamate 

Relevant articles and documents

Visible light-mediated synthesis of amides from carboxylic acids and amine-boranes

Here, a photocatalytic deoxygenative amidation protocol using readily available amine-boranes and carboxylic acids is described. This approach features mild conditions, moderate-to-good yields, easy scale-up, and up to 62 examples of functionalized amides with diverse substituents. The synthetic robustness of this method was also demonstrated by its application in the late-stage functionalization of several pharmaceutical molecules.

The Pd-catalyzed synthesis of difluoroethyl and difluorovinyl compounds with a chlorodifluoroethyl iodonium salt (CDFI)

Herein, we report a simple and efficient method for the direct installation of chlorodifluoroethyl group onto aromatic molecules of various aromatic amides with a new 2-chloro,2,2-difluoroethyl(mesityl)iodonium salt (CDFI). Moreover, the chlorodifluoroeth