1849-25-8 Usage
Description
(p-Aminophenyl)phenylacetylene, also known as 4-(Phenylethynyl)aniline, is an organic compound that has been synthesized through phosphine-free Sonogashira cross-coupling reactions using a palladium(II) phthalocyanine complex catalyst. (p-Aminophenyl)phenylacetylene is characterized by its unique structure, which includes an acetylene functional group and an amino group attached to a phenyl ring.
Uses
Used in Chemical Synthesis:
(p-Aminophenyl)phenylacetylene is used as a key intermediate in the synthesis of various organic compounds, particularly those with potential applications in the pharmaceutical and materials science industries. Its unique structure allows for further functionalization and modification, making it a versatile building block for the development of new molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (p-Aminophenyl)phenylacetylene is used as a starting material for the development of novel drugs with potential therapeutic applications. Its structural features can be exploited to design molecules with specific biological activities, such as those targeting cancer cells or other disease-related pathways.
Used in Materials Science:
(p-Aminophenyl)phenylacetylene is also used in the field of materials science for the development of new materials with unique properties. Its structural characteristics can be utilized to create materials with enhanced electronic, optical, or mechanical properties, which can be applied in various technological applications, such as sensors, displays, or energy storage devices.
Check Digit Verification of cas no
The CAS Registry Mumber 1849-25-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,4 and 9 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1849-25:
(6*1)+(5*8)+(4*4)+(3*9)+(2*2)+(1*5)=98
98 % 10 = 8
So 1849-25-8 is a valid CAS Registry Number.
1849-25-8Relevant articles and documents
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Sladkov,A.M. et al.
, (1963)
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Co3O4 nanoparticles embedded in triple-shelled graphitic carbon nitride (Co3O4/TSCN): a new sustainable and high-performance hierarchical catalyst for the Pd/Cu-free Sonogashira–Hagihara cross-coupling reaction
Ghodsinia, Sara S. E.,Akhlaghinia, Batool,Jahanshahi, Roya
, p. 3217 - 3244 (2021/05/17)
Inspired by the synthesis of triple-shelled periodic mesoporous organosilica hollow spheres, a straightforward and controllable approach for the preparation of Co3O4 NPs embedded in triple-shelled graphitic carbon nitride has been es
Decorated palladium nanoparticles on mesoporous organosilicate as an efficient catalyst for Sonogashira coupling reaction
Mohajer, Fatemeh,Mohammadi Ziarani, Ghodsi,Badiei, Alireza
, p. 589 - 601 (2020/09/17)
Abstract: Reforming mesoporous silica was provided by the reaction of SBA‐15 with (3-aminopropyl)triethoxysilane, the product of which was treated with furfural to give SBA-propyl-imine-furan. In the next step, palladium chloride was attached to the funct
Metal-Free and syn-Selective Hydrohalogenation of Alkynes through a Pseudo-Intramolecular Process
Asahara, Haruyasu,Mukaijo, Yusuke,Muragishi, Kengo,Iwai, Kento,Ito, Akitaka,Nishiwaki, Nagatoshi
, p. 5747 - 5755 (2021/10/20)
A new metal-free hydrohalogenation method for alkynes has been developed, which proceeds through a pseudo-intramolecular process. In this reaction, ethynylaniline serves as a substrate to quantitatively form an anilinium salt upon treatment with hydrochloric acid. The spatial proximity facilitates the efficient electrophilic addition of HCl to the ethynyl group in syn-mode, affording the corresponding chloroalkene without overaddition. This protocol was applied to HBr and HI, and the corresponding bromo- and iodoalkenes were obtained, respectively. The obtained chloroalkene was converted to tri-substituted alkenes possessing different aryl/alkynyl groups through Pd-catalyzed cross-coupling reactions.
