185345-83-9

Basic information

• Product Name: Benzenesulfonamide, 4-[1-bromo-2-(4-fluorophenyl)-2-oxoethyl]-
• CAS NO: 185345-83-9
• Molecular Formula: C14H11BrFNO3S
• Molecular Weight: 372.215
• Mol File: 185345-83-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 4-[1-bromo-2-(4-fluorophenyl)-2-oxoethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-[1-bromo-2-(4-fluorophenyl)-2-oxoethyl]-(185345-83-9)
• EPA Substance Registry System: Benzenesulfonamide, 4-[1-bromo-2-(4-fluorophenyl)-2-oxoethyl]-(185345-83-9)

Safety Data

• Hazardous Substances Data: 185345-83-9(Hazardous Substances Data)

Upstream product

• 395682-94-7 4-aminosulfonylphenylacetyl chloride 
• 103-80-0 phenylacetyl chloride 
• 185345-82-8 4-[2-(4-fluorophenyl)-2-oxoethyl]-1-benzenesulfonamide 
• 347-84-2 1-(4-fluorophenyl)-2-phenylethanone 
• 462-06-6 fluorobenzene 

Relevant articles and documents

1,2-Diaryl-1-ethanone and pyrazolo [4,3-c] quinoline-4-one as novel selective cyclooxygenase-2 inhibitors

Novel 1,2-diaryl-1-ethanone 1 and pyrazolo [4,3-c] quinoline-4-one 2, with pharmacophores different from the known COX inhibitors were identified as selective COX-2 inhibitors. The communication briefly describes SAR of both the series.

Substituted imidazo 1,2a}azines as selective inhibitors of cox-2

The invention refers to new compounds of formula (I), wherein A and B are selected from the group consisting of N and CH, with the condition that when A is N, B is N; R1is selected from the group consisting of CH3and NH2;