187222-17-9 Usage
Description
4-Chloro-2-ethoxycarbonyl-3,5-Lutidine is an organic compound with the molecular formula C10H10ClNO2. It is a derivative of lutidine, featuring a chlorine atom at the 4-position, an ethoxycarbonyl group at the 2-position, and a methyl group at both the 3 and 5 positions. 4-Chloro-2-ethoxycarbonyl-3,5-Lutidine is known for its potential applications in the pharmaceutical industry due to its unique structural properties.
Uses
Used in Pharmaceutical Industry:
4-Chloro-2-ethoxycarbonyl-3,5-Lutidine is used as an intermediate in the synthesis of various pharmaceutical compounds. Its specific application is in the production of Omeprazole (O635000), a medication that binds covalently to the proton pump, inhibiting gastric secretion. This makes it an effective antiulcerative agent, helping to treat conditions like gastroesophageal reflux disease (GERD) and peptic ulcers.
The compound's role in the synthesis of Omeprazole highlights its importance in the development of medications that address gastrointestinal issues. Its unique structural features allow for the creation of drugs with targeted effects, making it a valuable component in the pharmaceutical industry's efforts to combat ulcerative conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 187222-17-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,2,2 and 2 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 187222-17:
(8*1)+(7*8)+(6*7)+(5*2)+(4*2)+(3*2)+(2*1)+(1*7)=139
139 % 10 = 9
So 187222-17-9 is a valid CAS Registry Number.
187222-17-9Relevant articles and documents
Synthesis of pharmaceutically useful pyridine derivatives
-
, (2008/06/13)
A process is provided for the preparation of compounds of formula I, useful in the preparation of compounds such as Omeprazole, Lansoprazole and Pantoprazole, wherein R1=H or CH3, R2=H or CH3, R3=Alkoxy (1-4C), OCH2CF3, Cyano, Hydrogen, Halogen, Acetoxy or Aryloxy, any electron withdrawing group or salts (organic or inorganic) of electron donating groups, R=Alkoxy, Hydroxy, Halogen, Activated ester, Tosylate, Mesylate, Thiol or Xanthyl, wherein the process for the preparation of compound of formula I employs a free radical reaction to functionalize the 2-position.
