187463-12-3 Usage
Description
(E)-1-(2-bromovinyl)-2-fluorobenzen, also known as 2-fluoro-1-(2-bromovinyl)benzene, is a chemical compound characterized by the molecular formula C8H6BrF. It presents as a clear, colorless to yellow liquid with a distinct phenyl and vinyl odor. (E)-1-(2-bromovinyl)-2-fluorobenzen is recognized for its versatile applications across various industries, particularly in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Additionally, it serves as a fundamental building block in the production of polymers and acts as a reagent in organic synthesis processes.
Uses
Used in Pharmaceutical Industry:
(E)-1-(2-bromovinyl)-2-fluorobenzen is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications, contributing to the advancement of medical treatments.
Used in Agrochemical Industry:
In the agrochemical sector, (E)-1-(2-bromovinyl)-2-fluorobenzen is employed in the production of chemicals that serve to protect crops from pests and diseases. Its integration into the development of these chemicals aids in enhancing agricultural productivity and ensuring food security.
Used in Polymer Production:
(E)-1-(2-bromovinyl)-2-fluorobenzen acts as a crucial building block in the manufacturing of polymers. Its incorporation into the polymerization process leads to the creation of polymers with specific properties, such as enhanced strength, flexibility, or chemical resistance, which are essential for various applications in the plastics, coatings, and adhesives industries.
Used in Organic Synthesis:
As a reagent in organic synthesis, (E)-1-(2-bromovinyl)-2-fluorobenzen plays a significant role in the development of new organic compounds. Its participation in various chemical reactions enables the synthesis of a wide range of products, including specialty chemicals, dyes, and fragrances.
Safety Precautions:
Check Digit Verification of cas no
The CAS Registry Mumber 187463-12-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,4,6 and 3 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 187463-12:
(8*1)+(7*8)+(6*7)+(5*4)+(4*6)+(3*3)+(2*1)+(1*2)=163
163 % 10 = 3
So 187463-12-3 is a valid CAS Registry Number.
187463-12-3Relevant articles and documents
Cyclic Diaryl λ3-Bromanes: A Rapid Access to Molecular Complexity via Cycloaddition Reactions
Lanzi, Matteo,Ali Abdine, Racha Abed,De Abreu, Maxime,Wencel-Delord, Joanna
supporting information, p. 9047 - 9052 (2021/12/06)
Biaryls have widespread applications in organic synthesis. However, sequentially polysubstituted biaryls are underdeveloped due to their challenging preparation. Herein, we report the synthesis of dissymetric 2,3,2′,3′,4-substituted biaryls via pericyclic reactions of cyclic diaryl λ3-bromanes. The functional groups tolerance and atom economy allow access to molecular complexity in a single reaction step. Continuous flow protocol has been designed for the scale-up of the reaction, while postfunctionalizations have been developed taking advantage of the residual Br-atom.
Facile Synthesis of β-Bromostyrenes by Direct Bromination of Styrenes with N -Bromosuccinimide and Sodium Persulfate
Chen, Xuenian,Gao, Yan,Jing, Yi,Ma, Yan-Na,Zhao, Qianyi
supporting information, (2020/09/09)
A new, direct, efficient, and transition-metal-free method is reported for the synthesis of β-bromostyrenes from styrenes by using N -bromosuccinimide as the brominating reagent and sodium persulfate (Na 2S 2O 8) as the oxidant. This convenient and concise reaction is practical, operationally simple, and can be adapted for large-scale syntheses.
Synthesis of the Substituted Z-1-Bromo-1-alkenes and Arylacetylenes from 2,3-Dibromocarboxylic Acids
Matveeva,Erin,Kurz
, p. 1065 - 1067 (2007/10/03)
Stereoselectivity was studied of simultaneous debromination-decarboxylation of dibrominated cinnamic and acrylic acids. The best selectivity in formation of Z-vinyl bromides was achieved with the use of organic nitrogen bases. The 1-bromo-1-alkenes were converted into the corresponding acetylenes.
