187842-09-7

Basic information

• Product Name: Benzene, 1,1'-(chloromethylene)bis[3-fluoro-
• CAS NO: 187842-09-7
• Molecular Formula: C13H9ClF2
• Molecular Weight: 238.664
• Mol File: 187842-09-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-(chloromethylene)bis[3-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(chloromethylene)bis[3-fluoro-(187842-09-7)
• EPA Substance Registry System: Benzene, 1,1'-(chloromethylene)bis[3-fluoro-(187842-09-7)

Safety Data

• Hazardous Substances Data: 187842-09-7(Hazardous Substances Data)

Upstream product

• 98586-21-1 bis(3-fluorophenyl)methanol 
• 480460-90-0 ethyl 1-cyclohexyl-2-(2-fluoro-4-hydroxyphenyl)-1H-benzimidazole-5-carboxylate 
• 345-70-0 3,3'-difluorobenzophenone 

Relevant articles and documents

HETEROCYCLICALKYL DERIVATIVE COMPOUNDS AS SELECTIVE HISTONE DEACETYLASE INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME

The present invention relates to novel heterocyclicalkyl derivatives having histone deacetylase (HDAC) inhibitory activity, optical isomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel heterocyclicalkyl derivatives. The novel heterocyclicalkyl derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors, and may be effectively used for the treatment of histone deacetylase-mediated diseases, such as cell proliferative diseases, inflammatory diseases, autosomal dominant diseases, genetic metabolic diseases, autoimmune diseases, acute/chronic neurological disease, hypertrophy, heart failure, ocular diseases, or neurodegenerative diseases.

Fused-ring compounds and use thereof as drugs

The present invention provides a fused ring compound of the following formula [I] wherein each symbol is as defined in the specification, a pharmaceutically acceptable salt thereof, and a therapeutic agent for hepatitis C, which contains this compound. Th