188011-50-9Relevant articles and documents
The total synthesis of the natural product endothelin converting enzyme (ECE) inhibitor, WS75624 B
Patt, William C.,Massa, Mark A.
, p. 1297 - 1300 (1997)
The first total synthesis of WS75624 B, 1, an endothelin converting enzyme inhibitor produced in a fermentation broth of Saccharothrix sp. No. 75624 is reported herein. WS75624 B is synthesized in 14 steps from commercially available kojic acid, 2. The synthetic methodology allows for facile substitution at multiple sites on the molecule.