188198-38-1Relevant articles and documents
Kinetic Resolution of Racemic Primary Amines Using Geobacillus stearothermophilus Amine Dehydrogenase Variant
Tseliou, Vasilis,Knaus, Tanja,Vilím, Jan,Masman, Marcelo F.,Mutti, Francesco G.
, p. 2184 - 2188 (2020/03/11)
A NADH-dependent engineered amine dehydrogenase from Geobacillus stearothermophilus (LE-AmDH-v1) was applied together with a NADH-oxidase from Streptococcus mutans (NOx) for the kinetic resolution of pharmaceutically relevant racemic α-chiral primary amines. The reaction conditions (e. g., pH, temperature, type of buffer) were optimised to yield S-configured amines with up to >99 % ee.
Catalytic enantioselective borane reduction of benzyl oximes: Preparation of (S)-1-pyridin-3-YL-ethylamine bis hydrochloride
Huang, Kun,Ortiz-Marciales, Margarita,Hughes, David
scheme or table, p. 36 - 52 (2011/05/13)
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Enantioselective borohydride reduction of N-diphenylphosphinyl imines using optically active cobalt(II) complex catalysts
Sugi, Kiyoaki D.,Nagata, Takushi,Yamada, Tohru,Mukaiyama, Teruaki
, p. 493 - 494 (2007/10/03)
The enantioselective borohydride reduction using optically active cobalt(II) complex catalysts was successfully applied to various aryl N-diphenylphosphinyl imines, and the corresponding reduced products were obtained in good yields with high enantiomeric excesses (up to 99% ee). The optically active primary amines were obtained by the successive hydrolysis under mild conditions.