1882-69-5 Usage
Description
5-Methoxy-2-nitrobenzoic acid is a substituted 2-nitrobenzoic acid, characterized by its beige to grey or brown granules. It has been identified as one of the microbial degradation metabolites of cypermethrin, a synthetic pyrethroid pesticide.
Uses
Used in Pharmaceutical Industry:
5-Methoxy-2-nitrobenzoic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds for antitumor applications. It plays a crucial role in the production of Cathepsin S inhibitors, which are essential in the development of cancer treatments.
Used in Antimitotic Applications:
5-Methoxy-2-nitrobenzoic acid is also utilized in the synthesis of 2-aminocombretastatin derivatives, which have potential as antimitotic agents. These agents can disrupt the process of cell division, making them valuable in the development of cancer therapies.
Used in Neuroprotective Applications:
5-Methoxy-2-nitrobenzoic acid serves as a starting material in the synthesis of dictyoquinazol A, a neuroprotective compound that may offer potential benefits in the treatment of neurological disorders.
Used in Chemical Synthesis:
The compound is used as a starting material in the synthesis of 5-methoxyantranilic acid through catalytic reduction, which can be further utilized in various chemical and pharmaceutical applications.
Used in Pyrrolobenzodiazepine Synthesis:
Additionally, 5-Methoxy-2-nitrobenzoic acid is employed in the synthesis of pyrrolobenzodiazepines, a class of compounds with potential applications in various industries, including pharmaceuticals and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1882-69-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,8 and 2 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1882-69:
(6*1)+(5*8)+(4*8)+(3*2)+(2*6)+(1*9)=105
105 % 10 = 5
So 1882-69-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NO5/c1-14-5-2-3-7(9(12)13)6(4-5)8(10)11/h2-4H,1H3,(H,10,11)/p-1
1882-69-5Relevant articles and documents
Preparation method of anticoagulation drug intermediate 5-methoxy-2-nitrobenzoic acid
-
Paragraph 0026, (2017/08/28)
The invention discloses a preparation method of an anticoagulation drug intermediate 5-methoxy-2-nitrobenzoic acid and belongs to the field of drug intermediate synthesis. Cheap 3-drug intermediate serves as a raw material, a nitratlon reaction is selectively carried out at proper temperature to synthesize 5-chloro-2-nitrobenzoic acid, methyl alcohol is used for carrying out a substitution reaction on chlorine under the effect of alkali, and the needed intermediate 5-methoxy-2-nitrobenzoic acid is obtained. The preparation method which has short steps, simple reactions and low cost and can achieve stable industrial production is provided for a key intermediate of an anticoagulation drug Betrixaban.
1,2,5-THIAZOLIDINE DERIVATIVES USEFUL FOR TREATING CONDITIONS MEDIATED BY PROTEIN TYROSINE PHOSPHATASES (PTPASE)
-
Page/Page column 79, (2010/11/27)
-
The synthesis of a novel series of substituted 2-phenyl-4H-3,1- benzoxazin-4-ones
Pavlidis,Perry
, p. 533 - 548 (2007/10/02)
Following initial studies on a substituted 2-[3-methylphenyl]-4H-3,1- benzoxazin-4-one showing some cytotoxic activity, the synthesis of a novel series of 2-phenyl substituted 4H-3,1-benzoxazin-4-ones is reported herein.
