193481-76-4

Basic information

• Product Name: 3-Amino-5-methoxy-2-nitrobenzoic acid
• Synonyms: 3-Amino-5-methoxy-2-nitrobenzoic acid
• CAS NO: 193481-76-4
• Molecular Weight: 212.162
• Mol File: 193481-76-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Amino-5-methoxy-2-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-5-methoxy-2-nitrobenzoic acid(193481-76-4)
• EPA Substance Registry System: 3-Amino-5-methoxy-2-nitrobenzoic acid(193481-76-4)

Safety Data

• Hazardous Substances Data: 193481-76-4(Hazardous Substances Data)

Upstream product

• 67-62-9 O-Methylhydroxylamin 
• 320-98-9 5-fluoro-2-nitrobenzoic acid 
• 1882-69-5 5-methoxy-2-nitro-benzoic acid 

Downstream Products

• 1203473-77-1 2,3-diamino-5-methoxybenzoic acid 
• 1305323-74-3 3-amino-5-methoxy-2-nitro-benzoic acid methyl ester 

Relevant articles and documents

BENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS

Provided herein are sirtuin-modulating compounds of formula (II) The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

A convenient copper-catalyzed direct animation of nitroarenes with 9-alkylhydroxylamines

O-Alkylhydroxylamines, particularly O-methylhydroxylamine, aminate nitroarenes in the presence of a strong base and a copper catalyst to give aminonitroarenes in good yields, ortho- or para-Animation with respect to the nitro group takes place, and in some cases the ortho-aminated product is preferentially obtained. With 3-substituted nitrobenzenes where the substituent has a lone pair of electrons, preferential amination occurs at the 2-position to give the sterically most congested 3c-f, 14 and 22g.