188429-10-9

Basic information

• Product Name: (R)-2-{(R)-2-[(2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-oxo-tetrahydro-furan-3-yl]-pyrrolidin-1-yl}-3-hydroxy-3,3-diphenyl-propionic acid methyl ester
• CAS NO: 188429-10-9
• Molecular Weight: 553.771
• Mol File: 188429-10-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-{(R)-2-[(2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-oxo-tetrahydro-furan-3-yl]-pyrrolidin-1-yl}-3-hydroxy-3,3-diphenyl-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-{(R)-2-[(2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-oxo-tetrahydro-furan-3-yl]-pyrrolidin-1-yl}-3-hydroxy-3,3-diphenyl-propionic acid methyl ester(188429-10-9)
• EPA Substance Registry System: (R)-2-{(R)-2-[(2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-oxo-tetrahydro-furan-3-yl]-pyrrolidin-1-yl}-3-hydroxy-3,3-diphenyl-propionic acid methyl ester(188429-10-9)

Safety Data

• Hazardous Substances Data: 188429-10-9(Hazardous Substances Data)

Upstream product

• 119-61-9 benzophenone 
• 22041-18-5 methyl 2-(pyrrolidin-1-yl)acetate 
• 105122-15-4 (5S)-5-(tert-butyldimethylsilanyloxymethyl)-5H-furan-2-one 

Relevant articles and documents

An unexpected photoadduct of N-carbomethoxymethylpyrrolidine with a chiral butenolide and benzophenone: X-ray structure and synthetic utility

The regio- and stereoselective photoinduced addition of N-carbomethoxymethylpyrrolidine to 5(S)-tert-butyldimethylsiloxymethyl-furan-2(5H)-one in the presence of benzophenone yields 3(R)-[N-diphenylhydroxymethyl)carbomethoxymethylpyrrolidin- 2'-yl]-4(S)-tert-butyldimethylsiloxymethyl)-butan-4-olides (epimeric at C-2'), and we report the X-ray structure of the major adduct together with its conversion into the 1-azabicyclo[4.3.0]-nonane ring system.