188483-20-7

Basic information

• Product Name: Methanone, phenyl(3-phenyl-5-isothiazolyl)-
• CAS NO: 188483-20-7
• Molecular Formula: C16H11NOS
• Molecular Weight: 265.335
• Mol File: 188483-20-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Methanone, phenyl(3-phenyl-5-isothiazolyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, phenyl(3-phenyl-5-isothiazolyl)-(188483-20-7)
• EPA Substance Registry System: Methanone, phenyl(3-phenyl-5-isothiazolyl)-(188483-20-7)

Safety Data

• Hazardous Substances Data: 188483-20-7(Hazardous Substances Data)

Upstream product

• 955-83-9 2,5-diphenylfuran 
• 191402-10-5 triphenyl-λ⁶-sulfanenitrile 
• 855-31-2 1-(4-methoxyphenyl)-2,5-diphenyl-1H-pyrrole 
• 851-33-2 1,2,5-triphenyl-1H-pyrrole 
• 802-22-2 (2,5-diphenyl-pyrrol-1-yl)-carbamic acid tert-butyl ester 
• 857-30-7 1-(4-nitrophenyl)-2,5-diphenyl-1H-pyrrole 
• 94905-31-4 2,5-diphenyl-pyrrole-1-carboxylic acid methyl ester 
• 1445-78-9 2,5-Diphenyl-thiophene 

Relevant articles and documents

Reaction of furans with trithiazyl trichloride: New synthesis of isothiazoles

Trithiazyl trichloride 1 converts 2,5-disubstituted furans into isothiazoles (e.g. 3, 6, 7) regiospecifically and in good yield, providing a new, one-step synthesis of isothiazoles, for which a novel mechanism involving formation and ring-opening of a β-t

Generation of sulfenylnitrenes by N-sulfenylation of triphenyl-λ6-sulfanenitrile

The sulfenylation of triphenyl-λ6-sulfanenitrile (1) with 2,4-dinitrobenzenesulfenyl chloride in the presence of alkenes affords aziridines together with triphenylsulfonium salt. The reaction of 1 with sulfur dichloride also generates ClSN whic

Reaction of furans with trithiazyl trichloride: A new synthesis of isothiazoles

Trithiazyl trichloride 1 converts 2,5-diphenylfuran into 5-benzoyl-3-phenylisothiazole 2 regiospecifically and in high yield. This is a new ring opening of furans and a new synthesis of isothiazoles. 2,5-Bis(4-methylphenyl)furan, 3-bromo-2,5-diphenylfuran, 2,3,5-triphenylfuran, 2,5-di-tert-butylfuran and its 3-chloro and 3-bromo derivatives react in an entirely analogous manner to give the corresponding isothiazoles (55-85%) in synthetically useful, one-pot, conversions. 2,5-Diphenylthiophene reacts more slowly with the trimer 1 to give the same product, 2, as the corresponding furan, probably by oxidation of the analogous thiobenzoyl compound by the reagent, which is shown to oxidise thiobenzophenone to benzophenone very rapidly. Tetraphenylcyclopentadienone 8 reacts rapidly with the trimer to give 3,4,5,6-tetraphenyl-2(1H)-pyridone 10 (56%). Possible mechanisms in which the monomer, Cl-S≡N, is the reacting species are proposed for all of these reactions.