18879-86-2

Basic information

• Product Name: cyclohexanaminium cyclohexyldithiocarbamate
• CAS NO: 18879-86-2
• Molecular Formula: C₆H₁₃N*C₇H₁₃NS₂
• Molecular Weight: 274.4889
• Mol File: 18879-86-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 245.9°C at 760 mmHg
• Flash Point: 102.5°C
• Vapor Pressure: 0.028mmHg at 25°C
• CAS DataBase Reference: cyclohexanaminium cyclohexyldithiocarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: cyclohexanaminium cyclohexyldithiocarbamate(18879-86-2)
• EPA Substance Registry System: cyclohexanaminium cyclohexyldithiocarbamate(18879-86-2)

Safety Data

• Hazardous Substances Data: 18879-86-2(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 108-91-8 cyclohexylamine 
• 88-75-5 2-hydroxynitrobenzene 
• 591-27-5 m-Hydroxyaniline 
• 156-43-4 4-Ethoxyaniline 
• 95-55-6 2-amino-phenol 
• 104-94-9 4-methoxy-aniline 
• 123-30-8 4-amino-phenol 
• 137-26-8 Thiram 

Downstream Products

• 1212-29-9 1,3-dicyclohexylthiourea 
• 24070-58-4 N-cyclohexyl-N',N'-dimethylthiourea 
• 1122-82-3 isothiocyanatocyclohexane 
• 10450-11-0 N-cyclohexylbenzo[d]oxazol-2-amine 

Relevant articles and documents

Synthesis and Antimicrobial Activity of Methyl 2-(2-(2-Arylquinazolin-4-yl)sulfanyl)acetylamino Alkanoates

A series of methyl 2-(2-(2-arylquinazolin-4-yl)sulfanyl)acetylamino alkanoates have been developed on the basis of the S-chemoselective reaction of 2-arylquinazolin-4(3H)-thione with ethyl chloroacetate and N,N′-dicyclohexylcarbodiimide coupling method with amino acid ester hydrochloride. The precursor 2-arylquinazolin-4(3H)-thione was prepared by a new thiation method from 2-arylquinazolin-4(3H)-one by a two-step reaction that includes chlorination and then the reaction with N-cyclohexyldithiocarbamate cyclohexyl ammonium salt. The antimicrobial activity of the synthesized compounds was tested in vitro via paper-disc agar-plate method against two bacterial strains Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli and a pathogenic yeast Candida albicans. Most synthesized compounds showed remarkable antibacterial activity against E.?coli overpassing the standard reference antibiotics applied: tetracycline, erythromycin, and novobiocin. On the other hand, most synthesized compounds gave moderate antifungal activity against pathogenic yeast C.?albicans.

Cu-mediated one-pot three-component synthesis of 3-N-substituted 1,4,2-benzodithiazine 1,1-dioxide derivatives

A novel and efficient copper-catalyzed one-pot procedure for the synthesis of 3-N-substituted 1,4,2-benzodithiazine 1,1-dioxide derivatives from 2-halobenzenesulfonamides, amines and CS2 is described. The reaction proceeds through Ullmann-type S-arylation, intramolecular addition of NH2 with C[dbnd]S and dehydrosulfide, which provides a new and useful strategy for construction of cyclic aromatic sulfonamides.

Utilization of carbon disulfide as a powerful building block for the synthesis of 2-aminobenzoxazoles

This protocol describes a novel, mild and convenient route to afford 2-aminobenzoxazoles in high yields, and represents a significant advance towards an environmentally friendly strategy. Aliphatic amines are made to react with carbon disulfide to provide intermediate dithiocarbamates (DTC), which in the presence of 2-aminophenol, subsequently undergo successive intermolecular nucleophilic attack and desulfurization to produce 2-aminobenzoxazoles within 3 h.