188846-99-3 Usage
General Description
1-N-CBZ-3-CYANO-PYRROLIDINE is a chemical compound that is commonly used in the pharmaceutical industry as a building block in the synthesis of various drugs. It is a derivative of pyrrolidine, a heterocyclic organic compound, and contains a carbobenzyloxy (CBZ) and cyano group at the 1 and 3 positions, respectively. 1-N-CBZ-3-CYANO-PYRROLIDINE is known for its versatile reactivity and is used in the preparation of various pharmaceutical intermediates and bioactive compounds. Its unique structure and reactivity make it an important component in the development of new drugs and pharmaceutical products. This chemical is of great interest to the pharmaceutical industry due to its potential for use in the development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 188846-99-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,8,4 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 188846-99:
(8*1)+(7*8)+(6*8)+(5*8)+(4*4)+(3*6)+(2*9)+(1*9)=213
213 % 10 = 3
So 188846-99-3 is a valid CAS Registry Number.
188846-99-3Relevant articles and documents
Nitrilase-catalyzed enantioselective synthesis of pyrrolidine- And piperidinecarboxylic acids
Winkler, Margit,Meischler, Dorith,Klempier, Norbert
, p. 1475 - 1480 (2008/09/16)
The enantioselective synthesis of the nonproteinogenic amino acids β-proline and nipecotic acids from their readily available nitriles is achieved in high enantiomeric excess by commercially available nitrilases. The presented procedure comprises not more than 4 steps, thus considerably reducing the multiple steps generally required. Amide formation is also observed for specific heterocyclic nitriles.
Non-classical antifolates
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, (2008/06/13)
Compounds of the formula: in which:, Q is -OH or -NH2;, A is -CH2-, -CH2CH2-, -O-, or -S-;, -Ar- is a divalent aromatic ring;, W is -CO- or -SO2; and, Z is: (A) an α-amino acid group of the formula (B
