1890-28-4Relevant articles and documents
Five-Step Total Synthesis of (±)-Aspidospermidine by a Lactam Strategy via an Azomethine Ylide
Katahara, Seiya,Sugiyama, Yasukazu,Yamane, Mina,Komiya, Yukinori,Sato, Takaaki,Chida, Noritaka
, p. 3058 - 3063 (2021)
A five-step total synthesis of (±)-aspidospermidine (1) based on a lactam strategy is reported. Our synthesis features an iridium-catalyzed reductive Michael addition/[3+2] cycloaddition cascade to give a tricyclic ketone intermediate from a simple lactam via an azomethine ylide. The developed strategy enables easily available lactams to be used as stable surrogates of multisubstituted amines and would be applicable to a unified total synthesis of complex Aspidosperma alkaloids.
Reed
, p. 4116 (1962)
Preparation and structural investigations of new hexadentate Schiff base ligands and their bivalent metal complexes, and, catalytic applications of the complexes in allylic and benzylic C-H bond activation
Jyothi,Rao, G. Raghava,Shashank,Sridhar,Reddy, Anjali,Someshwar,Swamy, S. Jagannatha
, p. 535 - 544 (2014/05/06)
The reaction between 2-hydroxybenzaldehyde and piperazine-1,4-diylbis((2- aminophenyl)methanone) or N,N'-(ethane-1,2-diyl)bis(2-amino-N-methyl-benzamide) yields new hexadentate Schiff base ligands, (Z)-piperazine-1,4-diylbis((2-((Z)- (2-hydroxy-benzylidene)amino)phenyl)methanone) (PHMAPM) and 2-((2- hydroxybenzylidene)amino)-N-(2-(2-((E)-(2-hydroxybenzylidene)-amino) -N-methyl-benzimido)ethyl)-N-methylbenzamide (EHBAMB) respectively. PHMAPM crystallizes in the monoclinic space group P21/C. The Co(II), Ni(II) and Cu(II) complexes of these ligands have been prepared and characterized by elemental analyses, conductance, magnetic susceptibility and spectral investigations. The complexes are found to have the formula [M(PHMAPM)] and [M(EHBAMB)] respectively. The catalytic activity of these complexes in allylic and benzylic (C-H) activation has been investigated. The Cu(II) complexes are found to exhibit better activity in acetonitrile as compared to in other solvents.
Chemoenzymatic and enantiodivergent routes to 1,2-ring-fused bicyclo[2.2.2]octane and related tricyclic frameworks
Austin, Kerrie A. B.,Elsworth, Jon D.,Banwell, Martin G.,Willis, Anthony C.
supporting information; experimental part, p. 751 - 754 (2010/06/17)
New and simple protocols are described for the conversion of the enzymatically-derived and enantiomerically pure cis-1,2-dihydrocatechol 7 (X = I) and its 6-methylated derivative into either antipodal form of compounds embodying the tricyclic frameworks o
