1895-39-2

Basic information

• Product Name: Sodium chlorodifluoroacetate
• Synonyms: DIFLUOROCHLOROACETIC ACID SODIUM SALT;CHLORODIFLUOROACETIC ACID, NA;CHLORODIFLUOROACETIC ACID SODIUM;CHLORODIFLUOROACETIC ACID SODIUM SALT;SODIUM CHLORODIFLUOROACETATE;chlorodifluoro-aceticacisodiumsalt;Sodium chlorodifluoroacetate 97%;Sodiumchlorodifluoroacetate97%
• CAS NO: 1895-39-2
• Molecular Formula: C₂ClF₂O₂*Na
• Molecular Weight: 152.46
• EINECS: 217-586-0
• Product Categories: Pharmaceutical Intermediates;Fluorinated Building Blocks;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Synthetic Organic Chemistry;Miscellaneous Reagents
• Mol File: 1895-39-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 196-198 °C(lit.)
• Boiling Point: 119.2 °C at 760 mmHg
• Flash Point: 25.9 °C
• Appearance: White to off-white/Powder
• Density: 1.483g/cm3
• Vapor Pressure: 10.3mmHg at 25°C
• Storage Temp.: -20?C Freezer
• Solubility: Soluble in dimethoxyethane, diglyme (0.60 g mL-1), triglyme, dim
• BRN: 4162363
• CAS DataBase Reference: Sodium chlorodifluoroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium chlorodifluoroacetate(1895-39-2)
• EPA Substance Registry System: Sodium chlorodifluoroacetate(1895-39-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39-24/25-36/37/39
• WGK Germany: 3
• TSCA: T
• HazardClass: IRRITANT, HYGROSCOPIC
• Hazardous Substances Data: 1895-39-2(Hazardous Substances Data)

Usage

Description

Sodium chlorodifluoroacetate is a white to off-white powdery chemical compound, primarily recognized for its role as a pharmaceutical intermediate. It is known for its ability to facilitate the synthesis of 1,1-difluoro olefins through reactions with aldehydes and triphenylphosphine, making it a valuable component in the pharmaceutical industry.

Uses

Used in Pharmaceutical Industry:
Sodium chlorodifluoroacetate is used as a pharmaceutical intermediate for the synthesis of 1,1-difluoro olefins. This application is significant because it allows for a one-step synthesis process, which simplifies the production of these olefins and can potentially lead to more efficient and cost-effective pharmaceutical manufacturing.
The compound's role in the pharmaceutical industry is further emphasized by its ability to participate in a general reaction, making it a versatile and widely applicable intermediate for various chemical transformations and drug development processes.

InChI:InChI=1/C2HClF2O2.Na/c3-2(4,5)1(6)7;/h(H,6,7);/q;+1/p-1

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