35462-74-9

Basic information

• Product Name: 1-Nitro-3-(2,2,2-trifluoro-1-trifluoromethyl-ethyl)-benzene
• CAS NO: 35462-74-9
• Molecular Weight: 273.135
• Mol File: 35462-74-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Nitro-3-(2,2,2-trifluoro-1-trifluoromethyl-ethyl)-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Nitro-3-(2,2,2-trifluoro-1-trifluoromethyl-ethyl)-benzene(35462-74-9)
• EPA Substance Registry System: 1-Nitro-3-(2,2,2-trifluoro-1-trifluoromethyl-ethyl)-benzene(35462-74-9)

Safety Data

• Hazardous Substances Data: 35462-74-9(Hazardous Substances Data)

Upstream product

• 146500-61-0 3-nitro-β,β-difluoro-α-(trifluoromethyl)styrene 
• 645-00-1 m-iodonitrobenzene 
• 431-49-2 2-bromo-1,1,3,3,3-pentafluoropropene 
• 657-15-8 2,2,2-trifluoro-1-(3-nitrophenyl)ethanone 
• 1895-39-2 sodium chlorodifluoroacetate 

Relevant articles and documents

Preparation of β,β-Difluoro-α-(trifluoromethyl)styrenes by Palladium-Catalyzed Coupling of Aryl Iodides with Pentafluoropropen-2-ylzinc Reagent

Substituted aromatic iodides are functionalized by pentafluoropropen-2-ylzinc, CF3C(ZnX)=CF2 (X = Br, I, or CF2=CCF3-), in the presence of Pd(PPh3)4 to give the corresponding arenes in good yields.This is particularly attractive for the preparation of title styrenes substituted with groups such as -NO2 or CO2R, which are incompatible with organomagnesium reagents.The best yields of the title styrenes with electron-donating substituents were obtained in DMF.For electron-withdrawing substituents, the best results were achieved in triglyme.A correlation was observed between Hammett ? constants and 19F NMR chemical shifts (R = 0.93-0.99, n = 8) and 2JF-F coupling constants (R = 0.94, n = 8).