1897-53-6

Basic information

• Product Name: 2-FLUOROTEREPHTHALONITRILE
• Synonyms: 2-FLUOROTEREPHTHALONITRILE;3-Fluoroterephthalonitrile;2-Fluoro-1,4-benzenedicarbonitrile;2-Fluorobenzene-1,4-dicarbonitrile
• CAS NO: 1897-53-6
• Molecular Formula: C₈H₃FN₂
• Molecular Weight: 146.12
• Mol File: 1897-53-6.mol
• Article Data: 9

Chemical Properties

• Melting Point: 121.0-123.5 °C
• Boiling Point: 280.6°C at 760 mmHg
• Flash Point: 123.5°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 0.00376mmHg at 25°C
• Refractive Index: 1.538
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-FLUOROTEREPHTHALONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUOROTEREPHTHALONITRILE(1897-53-6)
• EPA Substance Registry System: 2-FLUOROTEREPHTHALONITRILE(1897-53-6)

Safety Data

• RIDADR: UN2811
• Hazardous Substances Data: 1897-53-6(Hazardous Substances Data)

Usage

General Description

2-Fluoroterephthalonitrile is a chemical compound with the molecular formula C8H3FNO2. It is a white crystalline solid with a molecular weight of 165.1 g/mol. 2-Fluoroterephthalonitrile is primarily used as an intermediate in the production of pharmaceuticals, agrochemicals, dyes, and pigments. It is also used in the manufacturing of polymers and as a building block in organic synthesis. The compound is considered to be moderately hazardous, with potential health effects including skin and eye irritation, respiratory irritation, and central nervous system effects. It is important to handle 2-Fluoroterephthalonitrile with care and follow proper safety precautions when working with this chemical.

InChI:InChI=1/C8H3FN2/c9-8-3-6(4-10)1-2-7(8)5-11/h1-3H

Upstream product

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Relevant articles and documents

Preparation method of aromatic dicarboxylic acid derivative

The invention provides a preparation method of an aromatic dicarboxylic acid derivative, wherein the preparation method comprises the following steps: step 1, carrying out a coupling reaction on dihalogenated aromatic hydrocarbon and metal cyanide at a temperature of 40-200 DEG C under metal catalysis in a solvent, and carrying out extraction layering concentration to obtain a dicyano compound after the reaction is finished; and step 2, carrying out a hydrolysis reaction on the obtained dicyanogen compound at the temperature of 60-200 DEG C under an acidic condition, and carrying out post-treatment to obtain the final product. According to the preparation method of the aromatic dicarboxylic acid derivative, dihalogenated aromatic hydrocarbon reacts with metal cyanide and then is hydrolyzedunder the acidic condition to obtain aromatic acid or the derivative thereof, and the preparation method has the remarkable advantages that the raw materials are cheap and easy to obtain, operation is easy and convenient, the yield is high, three wastes are easy to dispose, the product quality is high, and the substrate tolerance is good.

COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE

A compound is represented by a formula (1) below, in which k is an integer of 0 or more, m is an integer of 1 or more, n is an integer of 2 or more. L is a substituted or unsubstituted aromatic hydrocarbon ring having 6 to 30 ring carbon atoms, CN is a cyano group, and D1 and D2 are each independently represented by one of a formula (2), a formula (3) and formula (3x) below, D1 and D2 being optionally mutually the same or different.

ANTIPARASITIC AGENTS

The present invention relates to compounds of the formula (I) or a tautomer or prodrug thereof, or a pharmaceutically acceptable salt of said compound, tautomer or prodrug, wherein: R1, R2, R3, R4 and R5 are each independently selected from H, halo, CN, CF3 and CONH2; compositions containing such compounds and the uses of such compounds as antiparasitic agents.