19064-67-6Relevant articles and documents
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Taft et al.
, p. 605 (1961)
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NOVEL HYDRAZONE DERIVATIVE WITH ARYL OR HETEROARYL GROUP SUBSTITUTED AT TERMINAL AMINE GROUP THEREOF AND USE THEREOF
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Paragraph 0396, (2021/11/04)
The present invention relates to novel hydrazone derivatives in which a terminal amine group is substituted with an aryl group or a heteroaryl group, and uses thereof.
Pyridazine hydrazone derivative and preparation method and application thereof
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Paragraph 0035-0039, (2020/05/14)
The invention relates to a pyridazine hydrazone derivative shown as a chemical structural formula I and a pharmaceutically acceptable salt thereof, a pharmaceutical composition and application thereofin preparation of an influenza virus neuraminidase inhibitor, wherein Y is selected from the group consisting of: hydroxyl, dihydroxyl, 2-hydroxyl-3-methoxy, 2-hydroxyl-4-methoxy, 2-hydroxyl-5-methoxy, 2-hydroxyl-6-methoxy, 3-hydroxyl-2-methoxy, 3-hydroxyl-4-methoxy, 3-hydroxyl-5-methoxy, 3-hydroxyl-6-methoxy, 4-hydroxyl-2-methoxy, 4-hydroxyl-3-methoxy, 4-hydroxyl-3, 5-dimethoxy, 2-hydroxyl-3-ethoxy, 2-hydroxy-4-ethyoxyl, 2-hydroxy-5-ethyoxyl, 2-hydroxy-6-ethyoxyl, 3-hydroxy-2-ethyoxyl, 3-hydroxy-4-ethyoxyl, 3-hydroxy-5-ethyoxyl, 3-hydroxy-6-ethyoxyl, 4-hydroxy-2-ethyoxyl, 4-hydroxy-3-ethyoxyl, 4-hydroxy-3, 5-diethyoxyl, trihydroxy or 4-hydroxy-3, 5-dimethyl.
Intermolecular contacts in the crystal structures of specifically varied halogen and protonic group substituted azines
Hübscher, J?rg,Seichter, Wilhelm,Weber, Edwin
, p. 3026 - 3036 (2017/07/10)
A series of azines featuring differently halogen and protic group substituted pyridine, pyrimidine and pyridazine compounds have been synthesized and studied in terms of their crystal structures in order to develop a better understanding of the links between structural conditions and molecular packing behavior. Complemented by the structure results of related compounds known from the literature, intermolecular contact relationships connected to the present substance types were found, having potential use in future crystal engineering of similar compounds. This primarily involves the formation of N?I contacts aside from specific halogen?halogen and hydrogen bond type interactions.