50500-58-8

Basic information

• Product Name: 2-Benzyl-6-chloro-2H-pyridazin-3-one
• Synonyms: 2-Benzyl-6-chloro-2H-pyridazin-3-one
• CAS NO: 50500-58-8
• Molecular Formula: C₁₁H₉ClN₂O
• Molecular Weight: 220.65496
• Mol File: 50500-58-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Benzyl-6-chloro-2H-pyridazin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzyl-6-chloro-2H-pyridazin-3-one(50500-58-8)
• EPA Substance Registry System: 2-Benzyl-6-chloro-2H-pyridazin-3-one(50500-58-8)

Safety Data

• Hazardous Substances Data: 50500-58-8(Hazardous Substances Data)

Upstream product

• 19064-67-6 6-chloro-2H-pyridazin-3-one 
• 100-39-0 benzyl bromide 

Downstream Products

• 1005774-59-3 2-benzyl-6-(3-methylbut-1-ynyl)pyridazin-3(2H)-one 
• 909720-26-9 2-benzyl-6-(7-methoxy-3-methoxycarbonyl-2-isopropyl-pyrazolo[1,5-a]pyridine-4-yl)-3-(2H)-pyridazinone 
• 909720-27-0 2-benzyl-6-(3-carboxy-7-methoxy-2-isopropylpyrazolo[1,5-a]pyridine-4-yl)-3-(2H)-pyridazinone 
• 1616400-06-6 2-benzyl-6-(3,5-dimethylisoxazol-4-yl)pyridazin-3(2H)-one 
• 1616400-97-5 2-benzyl-6-((5,6-dimethoxypyridin-2-yl)amino)pyridazin-3(2H)-one 
• 1345839-68-0 2-benzyl-6-chloro-4-iodopyridazin-3(2H)-one 
• 1345839-67-9 2-benzyl-4-bromo-6-chloropyridazin-3(2H)-one 
• 1345839-65-7 2-benzyl-6-chloro-4-(pyrazin-2-yl)pyridazin-3(2H)-one 
• 1345839-57-7 ethyl 4-(2-benzyl-6-chloro-3-oxo-2,3-dihydropyridazin-4-yl)benzoate 
• 1345839-61-3 2-benzyl-6-chloro-4-(3-(trifluoromethyl)phenyl)pyridazin-3(2H)-one 
• 1345839-62-4 2-benzyl-6-chloro-4-(4-(trifluoromethyl)phenyl)pyridazin-3(2H)-one 
• 1260145-13-8 2-benzyl-6-chloro-4-(4-methoxyphenyl)pyridazin-3(2H)-one 
• 1345839-58-8 2-benzyl-6-chloro-4-(2-chlorophenyl)pyridazin-3(2H)-one 
• 1345839-59-9 2-benzyl-6-chloro-4-(3-chlorophenyl)pyridazin-3(2H)-one 

Relevant articles and documents

Novel Heterocyclic Compounds as Bromodomain Inhibitors

The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.

Concise routes to pyrazolo[1,5-a]pyridin-3-yl pyridazin-3-ones

Cycloaddition of pyridine N-imine with 6-alkyl-4-oxohex-5-ynoates followed by condensation with hydrazine provides concise access to pharmacologically active 6-(pyrazolo[1,5-a]pyridin-3-yl)pyridazinones. For the first time alkynyl heterocycles are also shown to be effective dipolarophiles for pyridine N-imine, and analogous compounds can be accessed directly in modest yields through the reaction of 6-(alkyn-1-yl)pyridazin-3-one derivatives. The Royal Society of Chemistry 2008.