191086-84-7

Basic information

• Product Name: Acetic acid (acetoxymethyl-methyl-{3-[4-(3-nitro-[1,2,4]triazol-1-yl)-2-oxo-2H-pyrimidin-1-yl]-propyl}-silanyl)-methyl ester
• Synonyms: Acetic acid (acetoxymethyl-methyl-{3-[4-(3-nitro-[1,2,4]triazol-1-yl)-2-oxo-2H-pyrimidin-1-yl]-propyl}-silanyl)-methyl ester
• CAS NO: 191086-84-7
• Molecular Weight: 438.472
• Mol File: 191086-84-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid (acetoxymethyl-methyl-{3-[4-(3-nitro-[1,2,4]triazol-1-yl)-2-oxo-2H-pyrimidin-1-yl]-propyl}-silanyl)-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (acetoxymethyl-methyl-{3-[4-(3-nitro-[1,2,4]triazol-1-yl)-2-oxo-2H-pyrimidin-1-yl]-propyl}-silanyl)-methyl ester(191086-84-7)
• EPA Substance Registry System: Acetic acid (acetoxymethyl-methyl-{3-[4-(3-nitro-[1,2,4]triazol-1-yl)-2-oxo-2H-pyrimidin-1-yl]-propyl}-silanyl)-methyl ester(191086-84-7)

Safety Data

• Hazardous Substances Data: 191086-84-7(Hazardous Substances Data)

Upstream product

• 74257-00-4 1-(mesitylene-2-sulfonyl)-3-nitro-1H-1,2,4-triazole 
• 191086-82-5 Acetic acid {acetoxymethyl-[3-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-propyl]-methyl-silanyl}-methyl ester 

Downstream Products

• 191086-92-7 N-{1-[3-(Bis-hydroxymethyl-methyl-silanyl)-propyl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-benzamide 
• 191086-95-0 N-[1-(3-{[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-hydroxymethyl-methyl-silanyl}-propyl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide 

Relevant articles and documents

Synthesis of silicon analogues of acyclonucleotides incorporable in oligonucleotide solid-phase synthesis

The synthesis of the four silicon analogues of acyclonucleosides was described. In every case, the silicon atom was introduced onto an allyl group on the natural nucleobase following a hydrosilylation reaction. Diols obtained were protected as 4,4'-dimethoxytrityl ethers and subsequently activated as 2-cyanoethyl N,N-diisopropylchlorophosphoramidite in order to be suitable for oligonucleotide solid phase synthesis.