1927-61-3

Basic information

• Product Name: tetrahydro-2-(2-phenylethoxy)-2H-pyran
• Synonyms: tetrahydro-2-(2-phenylethoxy)-2H-pyran;2-(2-Phenylethoxy)tetrahydro-2H-pyran;2-(Phenethyloxy)tetrahydro-2H-pyran;2-Phenylethyl(tetrahydro-2H-pyran-2-yl) ether;Phenethyl(tetrahydro-2H-pyran-2-yl) ether;Phenethyltetrahydro-2H-pyran-2-yl ether
• CAS NO: 1927-61-3
• Molecular Formula: C₁₃H₁₈O₂
• Molecular Weight: 206.28082
• EINECS: 217-666-5
• Mol File: 1927-61-3.mol
• Article Data: 62

Chemical Properties

• Boiling Point: 300.6°C at 760 mmHg
• Flash Point: 114.5°C
• Appearance: /
• Density: 1.03g/cm³
• Vapor Pressure: 0.00199mmHg at 25°C
• Refractive Index: 1.519
• CAS DataBase Reference: tetrahydro-2-(2-phenylethoxy)-2H-pyran(CAS DataBase Reference)
• NIST Chemistry Reference: tetrahydro-2-(2-phenylethoxy)-2H-pyran(1927-61-3)
• EPA Substance Registry System: tetrahydro-2-(2-phenylethoxy)-2H-pyran(1927-61-3)

Safety Data

• Hazardous Substances Data: 1927-61-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H18O2/c1-2-6-12(7-3-1)9-11-15-13-8-4-5-10-14-13/h1-3,6-7,13H,4-5,8-11H2

Upstream product

• 142-68-7 TETRAHYDROPYRANE 
• 60-12-8 2-phenylethanol 
• 69161-61-1 2-(prop-2-en-1-yloxy)oxane 
• 110-87-2 3,4-dihydro-2H-pyran 
• 14629-58-4 trimethyl(phenethyloxy)silane 
• 143888-88-4 2-(2-bromophenyl)ethyl tetrahydro-2H-pyran-2-yl ether 
• 694-54-2 tetrahydro-2H-2-pyranol 
• 126680-79-3 tert-butyldimethyl((tetrahydro-2H-pyran-2-yl)oxy)silane 

Downstream Products

• 60-12-8 2-phenylethanol 
• 133885-11-7 5-Phenethyloxy-pentan-1-ol 
• 104-62-1 formic acid phenethyl ester 
• 52767-51-8 (±)-2-phenethoxytetrahydrofuran 
• 4412-39-9 (2,2-dichloroethyl)benzene 
• 1943-82-4 phenethyl isocyanate 
• 6926-44-9 phenethyl azide 
• 5654-72-8 2-phenylethyl thiocyanate 
• 645-59-0 dihydrocinnamonitrile 
• 122-78-1 phenylacetaldehyde 
• 103-45-7 acetic acid phenethyl ester 
• 94-47-3 2-Phenylethyl benzoate 
• 20965-36-0 2-(phenylthio)tetrahydro-2H-pyran 
• 83711-12-0 5,5-bis(phenylthio)-1-pentanol 

Relevant articles and documents

Bronsted acidic ionic liquids: Fast, mild, and efficient catalysts for solvent-free tetrahydropyranylation of alcohols

Bronsted acidic ionic liquids as efficient and reusable catalysts for the protection of alcohols as tetrahydropyranyl (THP) ethers under solvent-free conditions at room temperature was investigated. Good to excellent yields were obtained at a faster rate over [BMIm][HSO4] or [BMIm][H2PO4]. Copyright Taylor & Francis, Inc.

Highly selective tetrahydropyranylation/dehydropyranylation of alcohols and phenols using porous phenolsulfonic acid-formaldehyde resin catalyst under solvent-free condition

An efficient protocol for solvent-free chemoselective tetrahydropyranylation/depyranylation of alcohols and phenols is reported herein using mesoporous Phenolsulfonic Acid Formaldehyde Resins as a heterogeneous acid catalyst. The catalyst successfully performed chemoselective protection and deprotection reactions of a wide range of substrates ranging from primary to secondary and tertiary alcohols and also phenols. The reactions were carried out at ambient temperature under solvent-free condition (SolFC) which resulted in high yields within a very short time. FT-IR, TEM, SEM, EDS and TG-DSC analysis techniques were employed to characterize the synthesized polymeric catalyst. The chemoselective nature of our method was confirmed using 13C DEPT-135 NMR studies. The polymer catalyst was found to be recoverable even after 10th catalytic cycle without much depreciation in its activity. The heterogeneity of the catalyst was verified by hot filtration method. Good yield, energy and cost- effective method, solvent-free protocol, mild reaction conditions, no inert atmosphere, metal-free heterogeneous polymer catalyst and excellent recoverability of the catalyst are notable milestones of the reported protocol.

Direct Conversion of TMS-ethers to THP-ethers Catalyzed by {[K.18-Crown-6]Br3}n

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