1941-09-9

Basic information

• Product Name: 2-methoxy-5-(prop-2-en-1-yl)phenol
• Synonyms: 1941-09-9; 3-Allyl-6-methoxyphenol; 5-Allyl-2-methoxyphenol; 5-Allylguaiacol; phenol, 2-methoxy-5-(2-propen-1-yl)-; Phenol, 2-methoxy-5-(2-propenyl)-; Phenol, 5-allyl-2-methoxy-
• CAS NO: 1941-09-9
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 164.2011
• Mol File: 1941-09-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 253.5°C at 760 mmHg
• Flash Point: 122.4°C
• Density: 1.05g/cm³
• Vapor Pressure: 0.0114mmHg at 25°C
• Refractive Index: 1.535
• CAS DataBase Reference: 2-methoxy-5-(prop-2-en-1-yl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-5-(prop-2-en-1-yl)phenol(1941-09-9)
• EPA Substance Registry System: 2-methoxy-5-(prop-2-en-1-yl)phenol(1941-09-9)

Safety Data

• Hazardous Substances Data: 1941-09-9(Hazardous Substances Data)

Upstream product

• 501-19-9 chavibetol 
• 108-24-7 acetic anhydride 
• 613-70-7 2-methoxyphenyl acetate 
• 183593-98-8 5-iodo-2-methoxyphenyl acetate 
• 24850-33-7 allyltributylstanane 

Downstream Products

• 501-19-9 chavibetol 
• 60444-56-6 3-acetoxy-4-methoxybenzoic acid 
• 645-08-9 Isovanillic acid 

Relevant articles and documents

Structure–activity relationships and docking studies of hydroxychavicol and its analogs as xanthine oxidase inhibitors

Hydroxychavicol (HC), which is obtained from the leaves of Piper betle LINN. (Piperaceae), inhibits xanthine oxidase (XO) with an IC50 value of 16.7μM, making it more potent than the clinically used allopurinol (IC50=30.7μM). Herein, a structure–activity relationship analysis of the polar part analogs of HC was conducted and an inhibitor was discovered with a potency 13 times that of HC. Kinetic studies have revealed that HC and its active analog inhibit XO in an uncompetitive manner. The binding structure prediction of these inhibitor molecules to the XO complex with xanthine suggested that both compounds (HC and its analog) could simultaneously form hydrogen bonds with xanthine and XO.