613-70-7

Basic information

• Product Name: 2-METHOXYPHENYL ACETATE
• Synonyms: O-ACETYLGUAIACOL;2-methoxy-phenoacetate;Eucol;o-Acetoxyanisole;o-Anisyl acetate;Phenol, o-methoxy-, acetate;Phenol,2-methoxy-,acetate;2-METHOXYPHENYL ACETATE 98+%
• CAS NO: 613-70-7
• Molecular Formula: C₉H₁₀O₃
• Molecular Weight: 166.17
• EINECS: 210-350-8
• Product Categories: Aromatic Esters
• Mol File: 613-70-7.mol
• Article Data: 61

Chemical Properties

• Melting Point: 31.5°C
• Boiling Point: 122-124 °C18 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.129 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0421mmHg at 25°C
• Refractive Index: n20/D 1.514(lit.)
• CAS DataBase Reference: 2-METHOXYPHENYL ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXYPHENYL ACETATE(613-70-7)
• EPA Substance Registry System: 2-METHOXYPHENYL ACETATE(613-70-7)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 613-70-7(Hazardous Substances Data)

Usage

Description

2-METHOXYPHENYL ACETATE is an organic compound with a distinct aromatic profile, characterized by its woody, guaiacol, smoky, astringent, and phenolic taste with vanillin and coumarin nuances. It is synthesized from guaiacol and excess acetic anhydride in the presence of trace amounts of H2SO4 and has an odor similar to that of guaiacol.

Uses

Used in Flavor and Fragrance Industry:
2-METHOXYPHENYL ACETATE is used as a flavoring agent for its woody, guaiacol, smoky, astringent, and phenolic taste characteristics, which can enhance the flavor profile of various food and beverage products.
2-METHOXYPHENYL ACETATE is also used as a fragrance ingredient for its unique aroma, which can add depth and complexity to perfumes and other scented products.
Used in Chemical Synthesis:
2-METHOXYPHENYL ACETATE can be used as a starting material or intermediate in the synthesis of various organic compounds, such as pharmaceuticals, agrochemicals, and other specialty chemicals, due to its versatile chemical structure and reactivity.
Used in Research and Development:
2-METHOXYPHENYL ACETATE can be employed as a research tool in the study of chemical reactions, mechanisms, and the development of new synthetic methods, as well as in the investigation of its potential applications in various fields, such as materials science, pharmaceuticals, and biotechnology.

Preparation

From guaiacol and excess acetic anhydride in the presence of trace amounts of H2SO4.

InChI:InChI=1S/C9H10O3/c1-7(10)12-9-6-4-3-5-8(9)11-2/h3-6H,1-2H3

Upstream product

• 58343-58-1 9,10-dihydro-9,10-dihydroxyanthracene 
• 36382-85-1 2-Methoxy-4-[2-(2-methoxy-phenoxy)-prop-(Z)-ylidene]-cyclohexa-2,5-dienone 
• 127-09-3 sodium acetate 
• 100-66-3 methoxybenzene 
• 7664-93-9 sulfuric acid 
• 108-24-7 acetic anhydride 
• 90-05-1 2-methoxy-phenol 
• 506-96-7 Acetyl bromide 
• 835-79-0 1-(benzyloxy)-2-methoxybenzene 
• 33035-41-5 2-(diacetoxyiodo)mesitylene 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 64-19-7 acetic acid 
• 579-74-8 2-Methoxyacetophenone 
• 32565-77-8 3-acetoxy-2-(2-methoxyphenoxy)-1-(3,4-dimethoxyphenyl)-1-propanone 

Downstream Products

• 4030-18-6 N-(acetyl)pyrrolidine 
• 90-05-1 2-methoxy-phenol 
• 1197-09-7 1-(3,4-dihydroxyphenyl)ethan-1-one 
• 53606-41-0 2-methoxy-5-nitrophenyl acetate 
• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 
• 6100-74-9 3-hydroxy-4-methoxyacetophenone 
• 25360-32-1 carbonyl bis(hydrido)tris(triphenylphosphine)ruthenium(II) 
• 185698-55-9 2-(3-hydroxy-4-methoxyphenyl)-1-(3',4',5'-trimethoxyphenyl)ethyne 
• 117048-62-1 combrestatin A₄ 
• 350685-31-3 4-Iodo-2-i-propoxyanisole 
• 183803-04-5 methyl (5-iodo-2-methoxy-phenoxy)acetate 
• 848653-50-9 5-(3-acetoxy-4-methoxy-phenyl)-4-hydroxy-pentanoic acid methyl ester 
• 848653-56-5 4-hydroxy-5-(3-hydroxy-4-methoxy-phenyl)-pentanoic acid 
• 848653-51-0 5-(3-hydroxy-4-methoxy-benzyl)-dihydro-furan-2-one 

Relevant articles and documents

Total Synthesis of the Ambigols: A Cyanobacterial Class of Polyhalogenated Natural Products

The first total synthesis of all members of the cyanobacterial natural product class of the ambigols is described. Key steps of the synthetic strategy are the formation of sterically demanding mono- and bis-iodonium salts to install the required biaryl ether structural elements and Suzuki cross-coupling giving straightforward access to the biaryl bonds. The synthetic methods are also utilized to construct unnatural or hypothetical ambigols that are still awaiting discovery from Nature.

Solvent-free Acetylation Procedure

-

Preparation method of plant growth regulation compound sodium nitrophenolate

The invention relates to the field of preparation of agricultural auxiliaries, in particular to a preparation method of plant growth regulation compound sodium nitrophenolate. According to the invention, acetyl chloride is adopted to replace acetic anhydride which is a precursor to serve as a protecting group for hydroxyl acetylation, so that the acquisition difficulty of process raw materials is reduced, and the production cost of 5-nitroguaiacol sodium salt is controlled; and besides, a phase transfer catalyst is applied to the hydrolysis reaction of 5-nitroacetyl guaiacol, so that the hydrolysis of the product can be effectively promoted, the yield of the hydrolysis reaction is greatly improved, and the overall yield of the 5-nitroguaiacol sodium salt is further improved. The prepared 5-nitroguaiacol sodium salt has the advantage of low cost, and as a main effective component of the compound sodium nitrophenolate, the 5-nitroguaiacol sodium salt can improve the market competitiveness of the compound sodium nitrophenolate product, avoid the behavior that the drug effect of the compound sodium nitrophenolate product is reduced due to the fact that the cost of the 5-nitroguaiacol sodium salt is high and the ratio is reduced by bad manufacturers, and make contribution for promoting the benign development of the market.