19427-36-2 Usage
Description
11a-Hydroxy-16,17a-epoxyprogesterone is a steroid hormone that functions as an analog of progesterone, a naturally occurring hormone produced by the corpus luteum. This off-white solid is characterized by its unique chemical structure, which includes a hydroxyl group at the 11-alpha position and an epoxy group at the 16,17-alpha positions. Its role in biological systems is primarily associated with the modulation of reproductive functions and potential implications in the etiology of certain cancers.
Uses
Used in Pharmaceutical Industry:
11a-Hydroxy-16,17a-epoxyprogesterone is utilized as a pharmaceutical agent for its ability to induce maturation and secretory activity of the uterine endothelium. This makes it a valuable component in treatments related to the reproductive system, particularly in managing menstrual disorders and promoting a healthy uterine environment.
Additionally, this steroid hormone is used as a suppressant of ovulation, which can be beneficial in contraceptive applications or in the management of conditions that involve hormonal imbalances.
Used in Cancer Research:
Due to its structural similarity to progesterone and its implication in the etiology of breast cancer, 11a-Hydroxy-16,17a-epoxyprogesterone serves as a crucial compound in cancer research. It aids scientists in understanding the complex interactions between hormones and cancer development, potentially leading to the discovery of novel therapeutic approaches and preventive strategies for breast cancer and possibly other hormone-related cancers.
Synthesis
11a-Hydroxy-16,17a-epoxyprogesterone can be prepared from diosgenin through the steps of ring-opening, acetylation, oxidation, hydrolysis, elimination, epoxidation, and oxidation.
Check Digit Verification of cas no
The CAS Registry Mumber 19427-36-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,4,2 and 7 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 19427-36:
(7*1)+(6*9)+(5*4)+(4*2)+(3*7)+(2*3)+(1*6)=122
122 % 10 = 2
So 19427-36-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H28O4/c1-11(22)21-17(25-21)9-15-14-5-4-12-8-13(23)6-7-19(12,2)18(14)16(24)10-20(15,21)3/h8,14-18,24H,4-7,9-10H2,1-3H3/t14-,15-,16+,17+,18+,19-,20-,21+/m0/s1
