197569-11-2 Usage
Description
N-Boc-4-(Cyanomethylene)piperidine, also known as 1-Boc-4-(cyanomethyl)piperidine, is a versatile chemical compound and a piperidine derivative. It features a Boc (tert-butoxycarbonyl) protecting group on the nitrogen atom and a cyanomethylene group attached to the piperidine ring. N-Boc-4-(Cyanomethylene)piperidine is widely used in the synthesis of pharmaceuticals and organic materials due to its reactivity and ability to introduce various functional groups into molecules, making it a valuable intermediate in the preparation of complex molecules.
Uses
Used in Pharmaceutical Industry:
N-Boc-4-(Cyanomethylene)piperidine is used as a building block in organic synthesis for the development of new pharmaceuticals. Its versatile reactivity allows for the introduction of different functional groups into molecules, facilitating the creation of complex and effective drug candidates.
Used in Agrochemical Industry:
In the agrochemical industry, N-Boc-4-(Cyanomethylene)piperidine serves as an intermediate in the synthesis of various agrochemicals. Its ability to be incorporated into complex molecules contributes to the development of innovative and effective products for agricultural applications.
Used in Organic Synthesis:
N-Boc-4-(Cyanomethylene)piperidine is utilized as a key intermediate in organic synthesis, enabling the construction of a wide range of organic compounds. Its unique structure and reactivity make it a valuable component in the synthesis of various organic materials, including those with potential applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 197569-11-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,7,5,6 and 9 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 197569-11:
(8*1)+(7*9)+(6*7)+(5*5)+(4*6)+(3*9)+(2*1)+(1*1)=192
192 % 10 = 2
So 197569-11-2 is a valid CAS Registry Number.
197569-11-2Relevant articles and documents
SUBSTITUTED 1H-IMIDAZO[1, 2-B]PYRAZOLE-3-CARBOXAMIDE AS BRUTON TYROSINE KINASE INHIBITORS
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Page/Page column 27-28, (2022/01/24)
This invention relates to a series of compounds 1H-imidazo [1, 2-b] pyrazole-3-carboxamide substituted represented by formula I used as kinase inhibitors, in particular BTK inhibitors (Bruton tyrosine kinase), and the methods of manufacture and use thereof for the treatment of an autoimmune disease, inflammatory disease, cancer and potentially allergies.
Triazolopyridine and imidazopyridine compounds as well as preparation method and medical application thereof
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Paragraph 0293-0297, (2020/07/13)
The invention relates to triazolopyridine and imidazopyridine compounds as well as a preparation method and medical application thereof. Particularly, the invention relates to a compound as shown in ageneral formula (I), a preparation method thereof and a
Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors
Brazzolotto, Xavier,Gobec, Stanislav,Gro?elj, Uro?,Knez, Damijan,Malikowska-Racia, Natalia,Meden, An?e,Nachon, Florian,Sa?at, Kinga,Svete, Jurij
, (2020/09/15)
A series of tryptophan-based selective nanomolar butyrylcholinesterase (BChE) inhibitors was designed and synthesized. Compounds were optimized in terms of potency, selectivity, and synthetic accessibility. The crystal structure of the inhibitor 18 in complex with BChE revealed the molecular basis for its low nanomolar inhibition (IC50 = 2.8 nM). The favourable in vitro results enabled a first-in-animal in vivo efficacy and safety trial, which demonstrated a positive impact on fear-motivated and spatial long-term memory retrieval without any concomitant adverse motor effects. Altogether, this research culminated in a handful of new lead compounds with promising potential for symptomatic treatment of patients with Alzheimer's disease.
