199007-40-4

Basic information

• Product Name: 3-Phenyl-2-(1-trityl-1H-imidazol-4-yl)-propionic acid
• Synonyms: 3-Phenyl-2-(1-trityl-1H-imidazol-4-yl)-propionic acid
• CAS NO: 199007-40-4
• Molecular Weight: 458.56
• Mol File: 199007-40-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Phenyl-2-(1-trityl-1H-imidazol-4-yl)-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenyl-2-(1-trityl-1H-imidazol-4-yl)-propionic acid(199007-40-4)
• EPA Substance Registry System: 3-Phenyl-2-(1-trityl-1H-imidazol-4-yl)-propionic acid(199007-40-4)

Safety Data

• Hazardous Substances Data: 199007-40-4(Hazardous Substances Data)

Upstream product

• 145133-11-5 methyl [1-(triphenylmethyl)-1H-imidazol-4-yl]acetate 
• 4200-46-8 (1H-imidazol-4-yl)-acetic acid methyl ester 
• 3251-69-2 imidazole-4-acetic acid hydrochloride 
• 199007-39-1 (±)-methyl 3-phenyl-2-(1-trityl-1H-imidazol-4-yl)propanoate 

Relevant articles and documents

A new type of carboxypeptidase A inhibitors designed using an imidazole as a zinc coordinating ligand

2-(4-Imidazoyl)hydrocinnamic acid (1) and its congeners (2-4) having different length of alkyl chain spacers between the imidazole ring and the α-carbon to the carboxylate of 1 have been designed, synthesized and evaluated as inhibitors for carboxypeptidase A to show that they are competitive inhibitors for the enzyme. Inhibitor 1 was most potent having the K(i) value of 0.8 μM. The present study demonstrates that imidazole ring is an effective zinc coordinating ligand that can be useful for the design of inhibitors for zinc proteases.