20145-09-9

Basic information

• Product Name: 9-phenyl-9H-purin-6-amine
• Synonyms: 9H-purin-6-amine, 9-phenyl-; 9-Phenyl-9H-purin-6-amine
• CAS NO: 20145-09-9
• Molecular Formula: C₁₁H₉N₅
• Molecular Weight: 211.2227
• Mol File: 20145-09-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 467.7°C at 760 mmHg
• Flash Point: 236.7°C
• Density: 1.44g/cm³
• Vapor Pressure: 6.36E-09mmHg at 25°C
• Refractive Index: 1.77
• CAS DataBase Reference: 9-phenyl-9H-purin-6-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 9-phenyl-9H-purin-6-amine(20145-09-9)
• EPA Substance Registry System: 9-phenyl-9H-purin-6-amine(20145-09-9)

Safety Data

• Hazardous Substances Data: 20145-09-9(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 66224-66-6 adenine 
• 66950-63-8 phenyl N,N-dimethylsulfamate 
• 65009-00-9 O-phenyl N,N-diethylcarbamate 
• 108-95-2 phenol 
• 1167987-42-9 8-bromo-9-phenyladenine 
• 28856-55-5 N⁶-(N,N-dimethylaminomethylidene)adenine 
• 98-80-6 phenylboronic acid 
• 127820-31-9 N⁴-phenyl-pyrimidine-4,5,6-triyltriamine; sulfate 
• 77287-34-4 formamide 
• 41259-65-8 6-chloro-N₄-phenylpyrimidine-4,5-diamine 
• 5470-24-6 6-Chloro-9-phenyl-9H-purine 

Downstream Products

• 1427272-57-8 8-chloro-9-phenyl-9H-purin-6-amine 
• 6334-42-5 1,9-dihydro-9-phenyl-6H-purin-6-one 

Relevant articles and documents

Copper-catalyzed cross-coupling reactions of nucleobases with arylboronic acids: An efficient access to N-arylnucleobases

An efficient avenue for the direct N-arylation of nucleobases with arylboronic acids that is catalyzed by simple copper salts was discovered. The N-arylnucleobases were obtained in excellent yields at room temperature within 45 min when methanol and water

Direct N9-arylation of purines with aryl halides

An efficient method for N-arylation of purines is reported. The N-arylation is catalysed by Cu(i) and 4,7-bis(2-hydroxyethylamino)-1,10-phenanthroline (BHPhen) in aqueous DMF or ethanol. The reaction generally proceeds with high selectivity for the N

Selective copper catalysed aromatic N-arylation in water

4,7-Dipyrrolidinyl-1,10-phenanthroline (DPPhen) was identified as an efficient ligand for copper catalysed selective aromatic N-arylation in water. N-Arylation of indoles, imidazoles and purines proceeds with moderate to excellent yields and complete selectivity over aliphatic amines. Aqueous medium and the possibility for low metal and ligand loadings give the process a benign environmental profile.